{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T07:43:13Z","timestamp":1695800593168},"reference-count":14,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,6,22]],"date-time":"2016-06-22T00:00:00Z","timestamp":1466553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The reliability of low\u2010risk and high\u2010risk criteria in evaluating febrile infants aged up to 60 days has been well documented. The aim of this study was to evaluate gender differences in the reliability of these criteria in order to exclude serious bacterial infection (<jats:styled-content style=\"fixed-case\">SBI<\/jats:styled-content>) in febrile infants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study used the Rochester risk criteria, the study group was divided into low\u2010 or high\u2010risk status for <jats:styled-content style=\"fixed-case\">SBI<\/jats:styled-content>, and the data were stratified by gender. <jats:styled-content style=\"fixed-case\">SBI<\/jats:styled-content> was defined as a urinary tract infection, bacteraemia, meningitis or bacterial enteritis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We enrolled 1896 infants (58.3% males), and <jats:styled-content style=\"fixed-case\">SBI<\/jats:styled-content>s were found in 10.6% of the males and 8% of the females (p = 0.21). The sensitivity of the risk criteria was 91.5% for the males and 73.4% (p &lt; 0.05) for the females, and the positive likelihood ratio was 2.64 in the males versus 2.14 in the females (p &lt; 0.001). A multivariable analysis showed that high\u2010risk male patients were more than two times more likely to develop a bacterial infection than high\u2010risk females.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The Rochester risk criteria had a significantly higher sensitivity and positive likelihood ratio in males. Our findings suggest that clinicians should take gender into account when evaluating febrile infants.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.13471","type":"journal-article","created":{"date-parts":[[2016,5,13]],"date-time":"2016-05-13T08:06:52Z","timestamp":1463126812000},"update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Using the Rochester criteria to evaluate infantile fever is more effective in males than females"],"prefix":"10.1111","volume":"105","author":[{"given":"Miri","family":"Dotan","sequence":"first","affiliation":[{"name":"Department of Pediatrics C Schneider Children's Medical Center Petach Tiqva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liat","family":"Ashkenazi\u2010Hoffnung","sequence":"additional","affiliation":[{"name":"Sackler Faculty of Medicine Tel Aviv University Tel Aviv Israel"},{"name":"Department of Pediatrics B Schneider Children's Medical Center Petach Tiqva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Havazelet","family":"Yarden\u2010Bilavsky","sequence":"additional","affiliation":[{"name":"Sackler Faculty of Medicine Tel Aviv University Tel Aviv Israel"},{"name":"Department of Pediatrics A Schneider Children's Medical Center Petach Tiqva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Amir","sequence":"additional","affiliation":[{"name":"Department of Pediatrics C Schneider Children's Medical Center Petach Tiqva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naama","family":"Tirosh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics A Schneider Children's Medical Center Petach Tiqva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meirav","family":"Mor","sequence":"additional","affiliation":[{"name":"Sackler Faculty of Medicine Tel Aviv University Tel Aviv Israel"},{"name":"Unit of Emergency Medicine Schneider Children's Medical Center Petach Tiqva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Efraim","family":"Bilavsky","sequence":"additional","affiliation":[{"name":"Department of Pediatrics C Schneider Children's Medical Center Petach Tiqva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,6,22]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2009.01469.x"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.108.2.311"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(85)80175-X"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(88)80312-3"},{"key":"e_1_2_12_6_1","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1542\/peds.94.3.390","article-title":"Febrile infants at low risk for serious bacterial infection\u2013an appraisal of the Rochester criteria and implications for management. 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