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It comprised seven studies published between 2007 and 2014 and covered 495 infants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Suppositories were ineffective in shortening the time to reach full enteral feeding, and the evidence on enemas was contradictory. Enemas and rectal stimulation did not shorten the time until complete meconium evacuation was reached. Further research into safe, effective interventions to accelerate meconium excretion is needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.13540","type":"journal-article","created":{"date-parts":[[2016,8,10]],"date-time":"2016-08-10T08:47:05Z","timestamp":1470818825000},"page":"1280-1287","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Enemas, suppositories and rectal stimulation are not effective in accelerating enteral feeding or meconium evacuation in low\u2010birthweight infants: a systematic review"],"prefix":"10.1111","volume":"105","author":[{"given":"Kim","family":"Kamphorst","sequence":"first","affiliation":[{"name":"Department of Neonatology Lucas Hospital Apeldoorn The Netherlands"},{"name":"Department of Gynecology, Obstetrics Reproductive Medicine and Children Deventer Hospital Deventer The Netherlands"},{"name":"Department Clinical Health Science University Utrecht Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ydelette","family":"Sietsma","sequence":"additional","affiliation":[{"name":"Department Clinical Health Science University Utrecht Utrecht The Netherlands"},{"name":"Department Viaa Christian University of Applied Sciences Zwolle The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annemieke J.","family":"Brouwer","sequence":"additional","affiliation":[{"name":"Department Clinical Health Science University Utrecht Utrecht The Netherlands"},{"name":"Intensive Care Neonatology Wilhelmina Children's Hospital University Medical Centre Utrecht Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J. 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