{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T04:45:34Z","timestamp":1780548334074,"version":"3.54.1"},"reference-count":16,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,10,9]],"date-time":"2016-10-09T00:00:00Z","timestamp":1475971200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Foundation Frimurare Barnhuset"},{"name":"Her Royal Highness Crown Princess Lovisa Foundation"},{"name":"S\u00e4llskapet barnav\u00e5rd Foundation"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Hirschsprung disease is a multifactorial disease, which is mainly treated during childhood. There is a risk of impaired bowel function for a long time after surgery, and its impact on adult life has not been well studied. This study assessed whether having Hirschsprung disease affected social parameters such as educational level and income.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This nationwide, population\u2010based cohort study included all patients with Hirschsprung disease, registered in the Swedish National Patient Register from 1964 and 2013, who were each matched by age and sex to ten individuals randomly selected from the Swedish Population Register. The study outcomes were the highest educational level and individual disposable income in 2013 registered by Statistics Sweden.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study comprised 389 patients and 3847 controls, both 76% male, with a median age of 25\u00a0years. There were no statistically significant differences in highest educational level between the groups (p\u00a0=\u00a00.327). The median individual disposable income was 142\u00a0200 (0\u2013817\u00a0200) Swedish Krona in the patient group and 159\u00a0000 (0\u20133\u00a0418\u00a0900) in the control group (p\u00a0=\u00a00.615).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The highest educational level and the individual disposable income did not differ between patients with Hirschsprung disease and controls, indicating that the disease had a low impact on these parameters.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.13594","type":"journal-article","created":{"date-parts":[[2016,9,17]],"date-time":"2016-09-17T14:06:41Z","timestamp":1474121201000},"page":"1508-1512","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Population\u2010based study shows that Hirschsprung disease does not have a negative impact on education and income"],"prefix":"10.1111","volume":"105","author":[{"given":"Anna L\u00f6f","family":"Granstr\u00f6m","sequence":"first","affiliation":[{"name":"Department of Women's and Children's Health Karolinska Institutet Stockholm Sweden"},{"name":"Division of Paediatric Surgery Astrid Lindgren Children's Hospital Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Svenningsson","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Karolinska Institutet Stockholm Sweden"},{"name":"Division of Paediatric Surgery Astrid Lindgren Children's Hospital Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agneta","family":"Nordenskj\u00f6ld","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Karolinska Institutet Stockholm Sweden"},{"name":"Division of Paediatric Surgery Astrid Lindgren Children's Hospital Karolinska University Hospital Stockholm Sweden"},{"name":"Center of Molecular Medicine Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Wester","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Karolinska Institutet Stockholm Sweden"},{"name":"Division of Paediatric Surgery Astrid Lindgren Children's Hospital Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,10,9]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015\u20104608"},{"key":"e_1_2_11_3_1","first-page":"279","article-title":"Additional anomalies in Hirschsprung's disease: an analysis based on the nationwide survey in Japan","volume":"41","author":"Ikeda K","year":"1986","journal-title":"Z Kinderchir"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2013.07.017"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2010.02.065"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2011.0081"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2015.06.014"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.13154"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-11-450"},{"key":"e_1_2_11_10_1","unstructured":"Statistiska central byr\u00e5n.Evaluering av utbildningsregistret. 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