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Clinical and laboratory data were collected from patient records.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We identified 137 <jats:styled-content style=\"fixed-case\">EONS<\/jats:styled-content> cases in Denmark and 101 in Norway. There were 35 culture\u2010confirmed <jats:styled-content style=\"fixed-case\">EONS<\/jats:styled-content> cases: 16% of the Danish cases and 13% of the Norwegian cases. <jats:italic>Staphylococcus aureus<\/jats:italic> was the most frequently detected pathogen in 11 cases (31%), followed by Group B streptococci in nine (26%) and <jats:italic>Escherichia coli<\/jats:italic> in six (17%). In 85% of the 238 cases, the empiric therapy comprised gentamicin and a beta\u2010lactam, namely ampicillin in Denmark and benzylpenicillin in Norway. Patients with positive blood cultures had higher C\u2010reactive protein levels than patients with negative blood cultures and higher sepsis\u2010attributable mortality. Lumbar punctures were performed more frequently in Denmark.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There were marginal differences in the management of <jats:styled-content style=\"fixed-case\">EONS<\/jats:styled-content> between units in Denmark and Norway, mainly in their choice of antibiotics and the use of lumbar punctures. <jats:italic>Staphylococcus aureus<\/jats:italic> was the most common pathogen.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.13698","type":"journal-article","created":{"date-parts":[[2016,12,9]],"date-time":"2016-12-09T14:01:51Z","timestamp":1481292111000},"page":"375-381","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Management of early\u2010onset neonatal sepsis differs in the north and south of Scandinavia"],"prefix":"10.1111","volume":"106","author":[{"given":"Martin","family":"Drageset","sequence":"first","affiliation":[{"name":"Paediatric Research Group Faculty of Health Sciences University of Troms\u00f8 Troms\u00f8 Norway"},{"name":"Nordland Hospital Vester\u00e5len Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jon Widding","family":"Fjalstad","sequence":"additional","affiliation":[{"name":"Paediatric Research Group Faculty of Health Sciences University of Troms\u00f8 Troms\u00f8 Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sven","family":"Mortensen","sequence":"additional","affiliation":[{"name":"Hans Christian Andersen Childrens Hospital Odense University Hospital Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claus","family":"Klingenberg","sequence":"additional","affiliation":[{"name":"Paediatric Research Group Faculty of Health Sciences University of Troms\u00f8 Troms\u00f8 Norway"},{"name":"Department of Paediatrics University Hospital of North Norway Troms\u00f8 Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,1,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2013.09.011"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2014-307656"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2007.120709"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000000906"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)90015-1"},{"key":"e_1_2_10_7_1","unstructured":"NORM\/NORM\u2010VET2013.Usage of Antimicrobial Agents and Occurrence of Antimicrobial resistance in Norway. 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