{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T22:01:57Z","timestamp":1759960917409},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,3,8]],"date-time":"2017-03-08T00:00:00Z","timestamp":1488931200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The main aim of this study was to examine the aetiology and the yield of brain imaging of children with site locked headaches (<jats:styled-content style=\"fixed-case\">SLH<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study was carried out at Queen's University Hospital, Essex,<jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content>, from August 2011 to August 2015 and focused on patients who were at least five years of age, had experienced at least five<jats:styled-content style=\"fixed-case\">SLH<\/jats:styled-content>attacks and had a normal neurological examination. Bilateral or alternating unilateral headaches were excluded. Data were collected prospectively, and the headache diagnosis was based on the International Classification of Headache Disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We identified 292 eligible patients (60% female) aged 5.1\u201317 years: 177 with unilateral<jats:styled-content style=\"fixed-case\">SLH<\/jats:styled-content>, 104 with occipital<jats:styled-content style=\"fixed-case\">SLH<\/jats:styled-content>and 11 with vertex<jats:styled-content style=\"fixed-case\">SLH<\/jats:styled-content>. Anterior headaches were the most frequent (n = 133), and the diagnoses included migraine (n = 192), tension type headaches (n = 30) and medication\u2010overuse headaches (n = 22). The headache was unspecified in 43 cases. Magnetic resonance imaging was normal in 96% of the 283\/292 scanned or showed a nonspecific, nonsignificant abnormality in 4%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Site locked headaches were most likely to be caused by primary headaches, particularly migraine. An<jats:styled-content style=\"fixed-case\">SLH<\/jats:styled-content>without abnormal neurological findings is unlikely to have an underlying sinister aetiology, and routine brain imaging is not required in such cases.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.13743","type":"journal-article","created":{"date-parts":[[2017,1,11]],"date-time":"2017-01-11T14:56:25Z","timestamp":1484146585000},"page":"791-795","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Site locked headaches in paediatric patients do not require routine brain imaging and rarely have a serious aetiology"],"prefix":"10.1111","volume":"106","author":[{"given":"MAS","family":"Ahmed","sequence":"first","affiliation":[{"name":"Paediatric Department Queen's University Hospital Essex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Grossman","sequence":"additional","affiliation":[{"name":"Department of Cardiology Great Ormond Street Hospital for Sick Children London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Rafique","sequence":"additional","affiliation":[{"name":"Paediatric Department Queen's University Hospital Essex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Momoh Ojewuyi","sequence":"additional","affiliation":[{"name":"Paediatric Department Queen's University Hospital Essex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413485658"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2008.01607.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0972-2327.41876"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-008-0075-1"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1993.hed3307381.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1994.hed3409526.x"},{"key":"e_1_2_10_8_1","first-page":"27","article-title":"Common migraine (\u201cmigraine without aura\u201d): localization of the initial pain of attack","volume":"8","author":"Sjaastad O","year":"1993","journal-title":"Funct Neurol"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1990.hed3011725.x"},{"issue":"2","key":"e_1_2_10_10_1","first-page":"S11","article-title":"Unilateral headaches and their relationship with cervicogenic headache","volume":"18","author":"Bono G","year":"2000","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-001-0029-7"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2003.00646.x"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.1992.1203165.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2007.01052.x"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2000.00029.x"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1129-2377-14-S1-P181"},{"key":"e_1_2_10_17_1","first-page":"1","article-title":"Evidence\u2010based assessment and treatment of acute headache in children and adolescents in ED","volume":"2","author":"Joseph MM","year":"2005","journal-title":"Emerg Med Pract"},{"key":"e_1_2_10_18_1","doi-asserted-by":"crossref","first-page":"P4.324","DOI":"10.1212\/WNL.82.10_supplement.P4.324","article-title":"Occipital headaches and neuroimaging in children","volume":"82","author":"Bear J","year":"2014","journal-title":"Neurology"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-013-2692-3"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.96.3.413"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2011.01845.x"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2004.067256"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.2310\/8000.2014.141409"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0317167100030638"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2000.040008629.x"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.202.3.9051039"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.1996.3602083.x"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2010.01728.x"},{"key":"e_1_2_10_29_1","unstructured":"NICE guideline \u2013 headaches in young people and adults.2013. 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