{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T06:44:46Z","timestamp":1695624286164},"reference-count":15,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,6,16]],"date-time":"2017-06-16T00:00:00Z","timestamp":1497571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p><jats:italic>Streptococcus pneumoniae<\/jats:italic> (<jats:italic>S. pneumoniae<\/jats:italic>) is sometimes implicated in neonatal bacterial meningitis. This study described the demographic, clinical and biological features of neonatal <jats:italic>S. pneumoniae<\/jats:italic> meningitis and compared pneumococcal and group B streptococcal (<jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content>) neonatal meningitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a case\u2013control study that compared neonates, aged one to 28 days with <jats:italic>S. pneumoniae<\/jats:italic> meningitis or <jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content> meningitis. Each case with <jats:italic>S. pneumoniae<\/jats:italic> was randomly matched to four control patients with <jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content> by age group and study year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From 2001 to 2013, the national French paediatric network, which comprises 227 paediatric wards, recorded 831 neonatal cases of meningitis. <jats:italic>S. pneumoniae<\/jats:italic> (n = 18, 2.2%) was the fifth infection cause after <jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content> (n = 464, 55.8%), <jats:italic>Escherichia coli<\/jats:italic> (n = 232, 27.9%), <jats:italic>Neisseria meningitidis<\/jats:italic> (n = 23, 2.8%) and <jats:italic>Listeria monocytogenes<\/jats:italic> (n = 20, 2.4%). Neonatal pneumococcal and <jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content> meningitis did not differ in demographic data or clinical and biological characteristics. All <jats:italic>S. pneumoniae<\/jats:italic> strains were fully susceptible to cefotaxime, and we observed a decrease of 13\u2010valent pneumococcal conjugate vaccine (<jats:styled-content style=\"fixed-case\">PCV<\/jats:styled-content>13) serotypes (88.9%\u201320.0%) after <jats:styled-content style=\"fixed-case\">PCV<\/jats:styled-content>13 implementation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Clinically and biologically, neonatal pneumococcal meningitis could not be distinguished from <jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content> cases. A herd effect of <jats:styled-content style=\"fixed-case\">PCV<\/jats:styled-content>13 implementation was suggested by the decrease in the prevalence of vaccine serotypes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.13919","type":"journal-article","created":{"date-parts":[[2017,5,16]],"date-time":"2017-05-16T08:16:38Z","timestamp":1494922598000},"page":"1915-1918","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Case\u2013control study shows that neonatal pneumococcal meningitis cannot be distinguished from group B Streptococcus cases"],"prefix":"10.1111","volume":"106","author":[{"given":"Alexandra","family":"Arfi","sequence":"first","affiliation":[{"name":"H\u00f4pital Intercommunal de Cr\u00e9teil Service de Gyn\u00e9cologie Obst\u00e9trique Universit\u00e9 Paris Est, Paris XII Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Cohen","sequence":"additional","affiliation":[{"name":"ACTIV \u2013 Association Clinique et Th\u00e9rapeutique Infantile du Val de Marne Saint\u2010Maur\u2010des\u2010Foss\u00e9s France"},{"name":"Universit\u00e9 Paris Est, IMRB \u2013 GRC GEMINI Cr\u00e9teil France"},{"name":"Clinical Research Center (CRC) Centre Hospitalier Intercommunal de Cr\u00e9teil Cr\u00e9teil France"},{"name":"Groupe de Pathologie Infectieuse P\u00e9diatrique (GPIP) Paris France"},{"name":"Unit\u00e9 Court S\u00e9jour, Petits Nourrissons, Service de N\u00e9onatologie Centre Hospitalier Intercommunal de Cr\u00e9teil Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuelle","family":"Varon","sequence":"additional","affiliation":[{"name":"National Reference Center for Pneumococci Laboratoire de Microbiologie Assistance Publique\u2010H\u00f4pitaux de Paris Hopital Europ\u00e9en Georges\u2010Pompidou Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phane","family":"B\u00e9chet","sequence":"additional","affiliation":[{"name":"ACTIV \u2013 Association Clinique et Th\u00e9rapeutique Infantile du Val de Marne Saint\u2010Maur\u2010des\u2010Foss\u00e9s France"},{"name":"Universit\u00e9 Paris Est, IMRB \u2013 GRC GEMINI Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phane","family":"Bonacorsi","sequence":"additional","affiliation":[{"name":"Sorbonne Paris Cit\u00e9 Universit\u00e9 Denis Diderot Paris France"},{"name":"Service de Microbiologie H\u00f4pital Robert\u2010Debr\u00e9, AP\u2010HP Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corinne","family":"Levy","sequence":"additional","affiliation":[{"name":"ACTIV \u2013 Association Clinique et Th\u00e9rapeutique Infantile du Val de Marne Saint\u2010Maur\u2010des\u2010Foss\u00e9s France"},{"name":"Universit\u00e9 Paris Est, IMRB \u2013 GRC GEMINI Cr\u00e9teil France"},{"name":"Clinical Research Center (CRC) Centre Hospitalier Intercommunal de Cr\u00e9teil Cr\u00e9teil France"},{"name":"Groupe de Pathologie Infectieuse P\u00e9diatrique (GPIP) Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,16]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000000451"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis934"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.66.5.603"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000000955"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.08.010"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1586\/erv.12.53"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-200003000-00021"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/12.3.416"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcped.2013.05.016"},{"key":"e_1_2_11_11_1","unstructured":"The European Committee on antimicrobial susceptibility testing. 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