{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T19:46:56Z","timestamp":1766087216897,"version":"3.37.3"},"reference-count":29,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,6,16]],"date-time":"2017-06-16T00:00:00Z","timestamp":1497571200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2017,6,16]],"date-time":"2017-06-16T00:00:00Z","timestamp":1497571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002341","name":"Suomen Akatemia","doi-asserted-by":"publisher","award":["114034","132595","267133"],"award-info":[{"award-number":["114034","132595","267133"]}],"id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008723","name":"Suomen L\u00e4\u00e4ketieteen S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008723","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006706","name":"Tampereen Tuberkuloosis\u00e4\u00e4ti\u00d6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006706","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Paediatr"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1111\/apa.13931","type":"journal-article","created":{"date-parts":[[2017,5,25]],"date-time":"2017-05-25T16:47:05Z","timestamp":1495730825000},"page":"1512-1518","source":"Crossref","is-referenced-by-count":21,"title":["Marked variability observed in inpatient management of bronchiolitis in three Finnish hospitals"],"prefix":"10.1111","volume":"106","author":[{"given":"Varpu","family":"Elenius","sequence":"first","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine; Turku University Hospital; Turku Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eija","family":"Bergroth","sequence":"additional","affiliation":[{"name":"Department of Paediatrics; Kuopio University Hospital; Kuopio Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petri","family":"Koponen","sequence":"additional","affiliation":[{"name":"Department of Paediatrics; Tampere University Hospital; Tampere Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sami","family":"Remes","sequence":"additional","affiliation":[{"name":"Department of Paediatrics; Kuopio University Hospital; Kuopio Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro A.","family":"Piedra","sequence":"additional","affiliation":[{"name":"Departments of Molecular Virology and Microbiology and Pediatrics; Baylor College of Medicine; Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janice A.","family":"Espinola","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine; Massachusetts General Hospital; Harvard Medical School; Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matti","family":"Korppi","sequence":"additional","affiliation":[{"name":"Department of Paediatrics; Tampere University Hospital; Tampere Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Carlos A.","family":"Camargo","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine; Massachusetts General Hospital; Harvard Medical School; Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuomas","family":"Jartti","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine; Turku University Hospital; Turku Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,16]]},"reference":[{"key":"10.1111\/apa.13931-BIB0001|apa13931-cit-0001","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1056\/NEJMra1413456","article-title":"Viral Bronchiolitis in Children","volume":"374","author":"Meissner","year":"2016","journal-title":"N Engl J Med"},{"key":"10.1111\/apa.13931-BIB0002|apa13931-cit-0002","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1542\/peds.2007-2087","article-title":"Increasing burden and risk factors for bronchiolitis-related medical visits in infants enrolled in a state health care insurance plan","volume":"122","author":"Carroll","year":"2008","journal-title":"Pediatrics"},{"key":"10.1111\/apa.13931-BIB0003|apa13931-cit-0003","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/INF.0b013e3182a5f324","article-title":"Temporal trends in emergency department visits for bronchiolitis in the United States, 2006 to 2010","volume":"33","author":"Hasegawa","year":"2014","journal-title":"Pediatr Infect Dis J"},{"key":"10.1111\/apa.13931-BIB0004|apa13931-cit-0004","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/apa.12881","article-title":"Hospitalisation costs for infant bronchiolitis are up to 20 times higher if intensive care is needed","volume":"104","author":"Heikkil\u00e4","year":"2015","journal-title":"Acta Paediatr"},{"key":"10.1111\/apa.13931-BIB0005|apa13931-cit-0005","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1097\/MOP.0000000000000090","article-title":"Recent evidence on the management of bronchiolitis","volume":"26","author":"Schroeder","year":"2014","journal-title":"Curr Opin Pediatr"},{"key":"10.1111\/apa.13931-BIB0006|apa13931-cit-0006","first-page":"CD001266","article-title":"Bronchodilators for bronchiolitis","volume":"6","author":"Gadomski","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1111\/apa.13931-BIB0007|apa13931-cit-0007","first-page":"CD006458","article-title":"Nebulised hypertonic saline solution for acute bronchiolitis in infants","volume":"7","author":"Zhang","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1111\/apa.13931-BIB0008|apa13931-cit-0008","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1001\/jama.2013.284921","article-title":"Glucocorticoids for acute viral bronchiolitis in infants and young children","volume":"311","author":"Fernandes","year":"2014","journal-title":"JAMA"},{"key":"10.1111\/apa.13931-BIB0009|apa13931-cit-0009","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1542\/peds.2014-1036","article-title":"Effectiveness of quality improvement in hospitalization for bronchiolitis: a systematic review","volume":"134","author":"Ralston","year":"2014","journal-title":"Pediatrics"},{"key":"10.1111\/apa.13931-BIB0010|apa13931-cit-0010","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1542\/peds.2013-2005","article-title":"Bronchiolitis management before and after the AAP guidelines","volume":"133","author":"Parikh","year":"2014","journal-title":"Pediatrics"},{"key":"10.1111\/apa.13931-BIB0011|apa13931-cit-0011","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1002\/ppul.22835","article-title":"Assessing the impact of national guidelines on the management of children hospitalized for acute bronchiolitis","volume":"49","author":"McCulloh","year":"2014","journal-title":"Pediatr Pulmonol"},{"key":"10.1111\/apa.13931-BIB0012|apa13931-cit-0012","doi-asserted-by":"crossref","first-page":"e1474","DOI":"10.1542\/peds.2014-2742","article-title":"Clinical practice guideline: the diagnosis, management, and prevention of bronchiolitis","volume":"134","author":"Ralston","year":"2014","journal-title":"Pediatrics"},{"key":"10.1111\/apa.13931-BIB0013|apa13931-cit-0013","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/j.jpeds.2014.05.057","article-title":"Variation in the management of infants hospitalized for bronchiolitis persists after the 2006 American Academy of Pediatrics bronchiolitis guidelines","volume":"165","author":"Florin","year":"2014","journal-title":"J Pediatr"},{"key":"10.1111\/apa.13931-BIB0014|apa13931-cit-0014","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1111\/apa.12671","article-title":"Diagnosis and treatment of bronchiolitis in Finnish and Swedish children's hospitals","volume":"103","author":"Mecklin","year":"2014","journal-title":"Acta Paediatr"},{"key":"10.1111\/apa.13931-BIB0015|apa13931-cit-0015","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1097\/INF.0000000000000313","article-title":"Hospital length-of-stay is associated with rhinovirus etiology of bronchiolitis","volume":"33","author":"Jartti","year":"2014","journal-title":"Pediatr Infect Dis J"},{"key":"10.1111\/apa.13931-BIB0016|apa13931-cit-0016","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.acap.2014.07.005","article-title":"Variability in inpatient management of children hospitalized with bronchiolitis","volume":"15","author":"Macias","year":"2015","journal-title":"Acad Pediatr"},{"key":"10.1111\/apa.13931-BIB0017|apa13931-cit-0017","doi-asserted-by":"crossref","first-page":"e492","DOI":"10.1542\/peds.2012-0444","article-title":"Prospective multicenter study of children with bronchiolitis requiring mechanical ventilation","volume":"130","author":"Mansbach","year":"2012","journal-title":"Pediatrics"},{"key":"10.1111\/apa.13931-BIB0018|apa13931-cit-0018","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1542\/peds.2005-1322","article-title":"A randomized trial of home oxygen therapy from the emergency department for acute bronchiolitis","volume":"117","author":"Bajaj","year":"2006","journal-title":"Pediatrics"},{"key":"10.1111\/apa.13931-BIB0019|apa13931-cit-0019","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/j.1553-2712.2007.00034.x","article-title":"Prospective multicenter study of the viral etiology of bronchiolitis in the emergency department","volume":"15","author":"Mansbach","year":"2008","journal-title":"Acad Emerg Med"},{"key":"10.1111\/apa.13931-BIB0020|apa13931-cit-0020","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/pai.12046","article-title":"Prednisolone reduces recurrent wheezing after first rhinovirus wheeze: a 7-year follow-up","volume":"24","author":"Lukkarinen","year":"2013","journal-title":"Pediatr Allergy Immunol"},{"key":"10.1111\/apa.13931-BIB0021|apa13931-cit-0021","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.jaci.2014.07.001","article-title":"Short- and long-term efficacy of prednisolone for first acute rhinovirus-induced wheezing episode","volume":"135","author":"Jartti","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"10.1111\/apa.13931-BIB0022|apa13931-cit-0022","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/apa.13162","article-title":"Finnish guidelines for the treatment of laryngitis, wheezing bronchitis and bronchiolitis in children","volume":"105","author":"Tapiainen","year":"2016","journal-title":"Acta Paediatr"},{"key":"10.1111\/apa.13931-BIB0023|apa13931-cit-0023","unstructured":"National Institute for Health and Care Excellence Bronchiolitis: diagnosis and management of bronchiolitis in children 2015 www.nice.org.uk\/guidance\/ng9"},{"key":"10.1111\/apa.13931-BIB0024|apa13931-cit-0024","doi-asserted-by":"crossref","first-page":"2286","DOI":"10.1056\/NEJMoa1301839","article-title":"Racemic adrenaline and inhalation strategies in acute bronchiolitis","volume":"368","author":"Skjerven","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1111\/apa.13931-BIB0025|apa13931-cit-0025","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/S2213-2600(15)00319-7","article-title":"Allergic diseases and the effect of inhaled epinephrine in children with acute bronchiolitis: follow-up from the randomised, controlled, double-blind, Bronchiolitis ALL trial","volume":"3","author":"Skjerven","year":"2015","journal-title":"Lancet Respir Med"},{"key":"10.1111\/apa.13931-BIB0026|apa13931-cit-0026","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/S2213-2600(15)00333-1","article-title":"Inhaled epinephrine does not shorten hospital stay for infants with bronchiolitis destined to develop repeated bronchospasm","volume":"3","author":"Zorc","year":"2015","journal-title":"Lancet Respir Med"},{"key":"10.1111\/apa.13931-BIB0027|apa13931-cit-0027","first-page":"CD004878","article-title":"Glucocorticoids for acute viral bronchiolitis in infants and young children","volume":"6","author":"Fernandes","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1111\/apa.13931-BIB0028|apa13931-cit-0028","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1016\/j.jaci.2004.09.020","article-title":"Atopic characteristics of children with recurrent wheezing at high risk for the development of childhood asthma","volume":"114","author":"Guilbert","year":"2004","journal-title":"J Allergy Clin Immunol"},{"key":"10.1111\/apa.13931-BIB0029|apa13931-cit-0029","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1097\/INF.0b013e31818ee0c1","article-title":"Bronchiolitis: age and previous wheezing episodes are linked to viral etiology and atopic characteristics","volume":"28","author":"Jartti","year":"2009","journal-title":"Pediatr Infect Dis J"}],"container-title":["Acta Paediatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fapa.13931","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/apa.13931\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T21:07:50Z","timestamp":1625432870000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apa.13931"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,16]]},"references-count":29,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017,9]]}},"URL":"https:\/\/doi.org\/10.1111\/apa.13931","archive":["Portico"],"relation":{},"ISSN":["0803-5253"],"issn-type":[{"type":"print","value":"0803-5253"}],"subject":[],"published":{"date-parts":[[2017,6,16]]}}}