{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T01:20:26Z","timestamp":1775784026192,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2017,8,9]],"date-time":"2017-08-09T00:00:00Z","timestamp":1502236800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Therapeutic hypothermia is standard of care in term infants with moderate\u2010to\u2010severe hypoxic\u2013ischaemic encephalopathy (<jats:styled-content style=\"fixed-case\">HIE<\/jats:styled-content>). The goal of this survey was to explore the attitudes of U.S. neonatologists caring for infants with <jats:styled-content style=\"fixed-case\">HIE<\/jats:styled-content> who fall outside of current guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Case\u2010based survey administered to members of the Section on Neonatal\u2010Perinatal Medicine of the American Academy of Pediatrics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 447 responses were analysed, a response rate of 19%. We found significant variability amongst U.S. neonatologists with regard to the use of therapeutic hypothermia for infants with <jats:styled-content style=\"fixed-case\">HIE<\/jats:styled-content> who fall outside standard inclusion criteria. Scenarios with the most variability included <jats:styled-content style=\"fixed-case\">HIE<\/jats:styled-content> in a late preterm infant and <jats:styled-content style=\"fixed-case\">HIE<\/jats:styled-content> following a postnatal code. Provision of therapeutic hypothermia outside of standard guidelines was not influenced by number of years in practice, neonatal intensive care type (<jats:styled-content style=\"fixed-case\">NICU<\/jats:styled-content>) or <jats:styled-content style=\"fixed-case\">NICU<\/jats:styled-content> size.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Significant variability in practice exists when caring for infants with <jats:styled-content style=\"fixed-case\">HIE<\/jats:styled-content> who do not meet standard inclusion criteria, emphasizing the need for continued and rigorous research in this area.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.13983","type":"journal-article","created":{"date-parts":[[2017,7,11]],"date-time":"2017-07-11T08:36:41Z","timestamp":1499762201000},"page":"1772-1779","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Neonatal therapeutic hypothermia outside of standard guidelines: a survey of U.S. neonatologists"],"prefix":"10.1111","volume":"106","author":[{"given":"Jennifer","family":"Burnsed","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Virginia Charlottesville VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1210-7043","authenticated-orcid":false,"given":"Santina A.","family":"Zanelli","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Virginia Charlottesville VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,8,9]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2004.06.014"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)17946-X"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcps050929"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0900854"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-2441"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2010.03.030"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2011.43"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.12784"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008480-200004000-00004"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-200109000-00017"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.WCB.0000123904.17746.92"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1203\/PDR.0b013e318174efdd"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.16058"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2004.06.015"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1411480"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-3412"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2011.186"}],"container-title":["Acta Paediatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fapa.13983","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apa.13983","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T18:57:26Z","timestamp":1696013846000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apa.13983"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,9]]},"references-count":17,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1111\/apa.13983"],"URL":"https:\/\/doi.org\/10.1111\/apa.13983","archive":["Portico"],"relation":{},"ISSN":["0803-5253","1651-2227"],"issn-type":[{"value":"0803-5253","type":"print"},{"value":"1651-2227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,9]]},"assertion":[{"value":"2017-03-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-07-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-08-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}