{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T14:41:01Z","timestamp":1772030461130,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,9,18]],"date-time":"2017-09-18T00:00:00Z","timestamp":1505692800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study described the characteristics and risk factors of neonates who developed retinopathy of prematurity (<jats:styled-content style=\"fixed-case\">ROP<\/jats:styled-content>) and severe treatable <jats:styled-content style=\"fixed-case\">ROP<\/jats:styled-content> in two Egyptian neonatal intensive care units (<jats:styled-content style=\"fixed-case\">NICU<\/jats:styled-content>s).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective cohort study comprised 108 preterm neonates who were screened for <jats:styled-content style=\"fixed-case\">ROP<\/jats:styled-content> after being admitted to the two <jats:styled-content style=\"fixed-case\">NICU<\/jats:styled-content>s run by Cairo University Hospital from June 2014 to May 2015. Patients were examined using digital fundus photography and indirect ophthalmoscopy was performed if <jats:styled-content style=\"fixed-case\">ROP<\/jats:styled-content> was detected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Retinopathy of prematurity occurred in 75 patients. Late\u2010onset sepsis, ventilation and hypercapnia were independently associated with <jats:styled-content style=\"fixed-case\">ROP<\/jats:styled-content>. Patients who developed severe treatable <jats:styled-content style=\"fixed-case\">ROP<\/jats:styled-content> had a younger gestational age (GA) than patients who did not develop <jats:styled-content style=\"fixed-case\">ROP<\/jats:styled-content> or developed mild or moderate <jats:styled-content style=\"fixed-case\">ROP<\/jats:styled-content> (29 weeks, range 27\u201333 weeks versus 32 weeks, range 28\u201336 weeks, p = 0.002) and a lower birthweight (1200 g, range 980\u20131590 g versus 1460 g, range 770\u20132475 g, p = 0.029). The risk factors associated with severe treatable <jats:styled-content style=\"fixed-case\">ROP<\/jats:styled-content> included the duration of admission, the duration of incubator oxygen, late\u2010onset sepsis, intraventricular haemorrhage, total parenteral nutrition and the duration of caffeine citrate therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study showed that the risks for ROP were wide\u2010ranging and included GA and weight, medical conditions and treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.14019","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T07:52:43Z","timestamp":1502437963000},"page":"1919-1927","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Retrospective cohort study shows that the risks for retinopathy of prematurity included birth age and weight, medical conditions and treatment"],"prefix":"10.1111","volume":"106","author":[{"given":"Aliaa A.","family":"Ali","sequence":"first","affiliation":[{"name":"Department of Paediatrics Faculty of Medicine Cairo University Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy A.S.","family":"Gomaa","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Faculty of Medicine Cairo University Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed R.","family":"Awadein","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Faculty of Medicine Cairo University Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huda H.","family":"Al\u2010Hayouti","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Faculty of Medicine Cairo University Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed 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