{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T08:44:12Z","timestamp":1765356252142},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,9,17]],"date-time":"2017-09-17T00:00:00Z","timestamp":1505606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>We aimed to evaluate mortality and short\u2010term neonatal morbidity of babies born \u2264500 g cared for in the Northern Neonatal Network over a 15\u2010year period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Using regional databases, we identified all live\u2010born babies \u226522 weeks gestation and \u2264500 g, in North East England and North Cumbria from 1998 to 2012. We quantified major neonatal morbidities and survival to one year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We identified 104 live\u2010born babies \u226522 weeks gestation and \u2264500 g (birth prevalence 0.22\/1000), of which 49 were admitted for intensive care. Overall one\u2010year survival was 11%, but survival for those receiving intensive care was 22%. There was significant short\u2010term neonatal morbidity in survivors, in particular retinopathy of prematurity and chronic lung disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Survival of babies born weighing \u2264500 g in this cohort remains poor despite advances in neonatal care, with considerable short\u2010term neonatal morbidity in survivors. This could be due to a combination of attitudes and a rather conservative approach towards resuscitation and intensive care, and the intrinsic nature of these tiny babies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.14024","type":"journal-article","created":{"date-parts":[[2017,9,18]],"date-time":"2017-09-18T14:23:25Z","timestamp":1505744605000},"page":"223-226","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Outcomes of infants with a birthweight less than or equal to 500 g in Northern England: 15 years experience"],"prefix":"10.1111","volume":"107","author":[{"given":"Jenna","family":"Gillone","sequence":"first","affiliation":[{"name":"Newcastle Neonatal Service Royal Victoria Infirmary Newcastle Upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nishant","family":"Banait","sequence":"additional","affiliation":[{"name":"Newcastle Neonatal Service Royal Victoria Infirmary Newcastle Upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Miller","sequence":"additional","affiliation":[{"name":"Public Health England Newcastle Upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Ward Platt","sequence":"additional","affiliation":[{"name":"Newcastle Neonatal Service Royal Victoria Infirmary Newcastle Upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sundeep","family":"Harigopal","sequence":"additional","affiliation":[{"name":"Newcastle Neonatal Service Royal Victoria Infirmary Newcastle Upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,9,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2009.171629"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-12-17"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2015.44"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2006.09.014"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/sper.2001.27164"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1605566"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.771"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.10244"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.6.1559"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-2742"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(98)70037-7"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.319.7217.1093"},{"key":"e_1_2_10_14_1","unstructured":"Public Health England.Regional Maternity Survey Office 28th Annual Report 2015."},{"key":"e_1_2_10_15_1","doi-asserted-by":"crossref","first-page":"c2587","DOI":"10.1136\/bmj.c1140","article-title":"Using the new UK\u2010WHO growth charts","volume":"340","author":"Wright CM","year":"2010","journal-title":"BMJ"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.99.6.e7"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.101.3.438"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e7976"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.12414"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-2399"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2005.tb01893.x"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1410689"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2014.3351"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-2857"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-2988"},{"key":"e_1_2_10_26_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpeds.2017.05.017","article-title":"Early mortality and morbidity in infants with birth weight of 500\u2009grams or less in Japan","author":"Inoue H","year":"2017","journal-title":"J Ped"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.12633"},{"key":"e_1_2_10_28_1","unstructured":"Nuffield Council on Bioethics Critical care decisions in fetal and neonatal medicine: ethical issues.London:Nuffield Council on Bioethics 2006. 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