{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T15:07:11Z","timestamp":1760800031094},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,9,25]],"date-time":"2017-09-25T00:00:00Z","timestamp":1506297600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>We compared neonatal deaths and end\u2010of\u2010life decisions in a neonatal intensive care unit (NICU) and paediatric intensive care unit (PICU) in a Dutch tertiary children's hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects<\/jats:title><jats:p>All 235 full\u2010term infants who died within 28\u00a0days of life between 2003 and 2013 in the NICU (n\u00a0=\u00a0199) and PICU (n\u00a0=\u00a036) were retrospectively studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median length of stay was three days in the NICU and seven days in the PICU (p\u00a0=\u00a00.003). The main reasons for NICU stays were asphyxia (52.8%) and congenital malformations (42.2%), and in the PICU, they were congenital malformations (97.2%) and primarily cardiac problems (83.3%, p\u00a0&lt;\u00a00.001). The median age of death was three days in the NICU and eight days in the PICU (p\u00a0&lt;\u00a00.001), and mortality despite full intensive care treatment was 4.0% and 25.0%, respectively. Intensive treatment was discontinued because of poor survival chances in 25.1% of NICU and 52.8% of PICU cases (p\u00a0&lt;\u00a00.001), and care was redirected because of expected poor quality of life in 70.9% and 22.2%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Differences between the age at death and end\u2010of\u2010life decisions were found between full\u2010term infants in the NICU and PICU in the same children's hospital. Underlying disorders and doctors\u2019 attitudes may have played a role.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.14061","type":"journal-article","created":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T01:56:47Z","timestamp":1504576607000},"page":"270-275","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Deaths and end\u2010of\u2010life decisions differed between neonatal and paediatric intensive care units at the same children's hospital"],"prefix":"10.1111","volume":"107","author":[{"given":"Maartje C.","family":"Snoep","sequence":"first","affiliation":[{"name":"Department of Neonatology The Wilhelmina Children's Hospital University Medical Center Utrecht Utrecht University Utrecht the Netherlands"},{"name":"Paediatric Intensive Care The Wilhelmina Children's Hospital University Medical Center Utrecht Utrecht University Utrecht the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolaas J.G.","family":"Jansen","sequence":"additional","affiliation":[{"name":"Paediatric Intensive Care The Wilhelmina Children's Hospital University Medical Center Utrecht Utrecht University Utrecht the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Floris","family":"Groenendaal","sequence":"additional","affiliation":[{"name":"Department of Neonatology The Wilhelmina Children's Hospital University Medical Center Utrecht Utrecht University Utrecht the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,9,25]]},"reference":[{"key":"e_1_2_11_2_1","first-page":"106","article-title":"Neonatal deaths: prospective exploration of the causes and process of end\u2010of\u2010life decisions","volume":"2","author":"Hellmann J","year":"2016","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)71048-5"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2004.00398.x"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2009.166"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2009.07.019"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2015.00225"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269216316634246"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2011.607561"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyg163"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0080-6234201400005000002"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01957272"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-7-926"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.7.843"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02378-3"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-011-2357-3"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)80946-1"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)61030-6"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2014-306666"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2015-308659"},{"key":"e_1_2_11_21_1","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1089\/jpm.2015.29000.rbvl","article-title":"End\u2010of\u2010life Decisions in Pediatric Cancer Patients","volume":"18","author":"Loenhout RB","year":"2015","journal-title":"J Palliat Med"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-0780"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2013.07.007"},{"key":"e_1_2_11_24_1","volume-title":"Doen of laten? 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