{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T10:41:43Z","timestamp":1790419303318,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,1,25]],"date-time":"2018-01-25T00:00:00Z","timestamp":1516838400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100010810","name":"\u00d6gonfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010810","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To identify possible predictive factors for visual problems at 6.5\u00a0years in children born very preterm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>During 2004\u20132007, all very preterm infants (gestational age [GA] &lt;32\u00a0weeks) in Uppsala County, Sweden were screened for retinopathy of prematurity (ROP) neonatally; at four months, visual tracking was tested; at 2.5\u00a0years, visuospatial and cognitive tests were carried out. At 6.5\u00a0years, 84 preterm children and a reference group of 64 full\u2010term children underwent ophthalmological testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean visual acuity (VA) did not differ between the groups, but subnormal VA (\u22640.8) was more common in the preterm group (31% vs 14%; p\u00a0&lt;\u00a00.05). More often than full\u2010term children, preterm children had impaired contrast sensitivity (&lt;0.5) (36% vs 19%; p\u00a0&lt;\u00a00.05) and strabismus (8% vs 0%; p\u00a0&lt;\u00a00.05). Low GA, ROP, intraventricular haemorrhage 3\u20104\/periventricular leukomalacia and cognitive disability at 2.5\u00a0years predicted ophthalmological and visual problems at 6.5\u00a0years. Visual tracking ability at four months was not predictive of ophthalmological outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Children born preterm had more ophthalmological problems at 6.5\u00a0years of age, including subtle dysfunctions. ROP, early brain injury and impaired cognitive function around 2.5\u00a0years predicted later ophthalmological dysfunctions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.14209","type":"journal-article","created":{"date-parts":[[2017,12,30]],"date-time":"2017-12-30T01:42:34Z","timestamp":1514598154000},"page":"822-830","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Impaired cognitive ability at 2.5\u00a0years predicts later visual and ophthalmological problems in children born very preterm"],"prefix":"10.1111","volume":"107","author":[{"given":"Jonina","family":"Hreinsdottir","sequence":"first","affiliation":[{"name":"Department of Neuroscience Ophthalmology Uppsala University Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ylva","family":"Fredriksson Kaul","sequence":"additional","affiliation":[{"name":"Department of Woman and Children Uppsala University Uppsala 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