{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:22:19Z","timestamp":1762507339369,"version":"3.37.3"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,2,27]],"date-time":"2018-02-27T00:00:00Z","timestamp":1519689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Children's Memorial Health Institute, the Polish Ministry of Science and Higher Education","award":["224\/13"],"award-info":[{"award-number":["224\/13"]}]},{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"crossref","award":["POIG.02.01.00-14-059\/09"],"award-info":[{"award-number":["POIG.02.01.00-14-059\/09"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Children with ultra\u2010short bowel syndrome (<jats:styled-content style=\"fixed-case\">USBS<\/jats:styled-content>) have not been extensively studied to date because the condition is rare. The aim of the study was to assess the nutritional status of children with <jats:styled-content style=\"fixed-case\">USBS<\/jats:styled-content> receiving home parenteral nutrition, using citrulline serum concentration and cholestasis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We studied 17 patients with <jats:styled-content style=\"fixed-case\">USBS<\/jats:styled-content>, with a median age of 6.6 years and median duration of parenteral nutrition of 6.6 years. The study was carried out at The Children's Memorial Health Institute, Warsaw, from January 2014 to January 2015.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median standard deviation score (<jats:styled-content style=\"fixed-case\">SDS<\/jats:styled-content>) was \u22121.2 for body mass according to chronological age, \u22121.72 according to height and \u22120.59 according to height for age. Patients requiring seven days per week parenteral nutrition had a citrulline concentration below 10 <jats:italic>\u03bc<\/jats:italic>mol\/L. Decreased bone\u2010mineral density was observed in 87% of the patients. Low values of 25\u2010hydroxyvitamin D were found in 53% of the children. None of the patients had elevated conjugated bilirubin levels above 34.2 <jats:italic>\u03bc<\/jats:italic>mol\/L.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Children with <jats:styled-content style=\"fixed-case\">USBS<\/jats:styled-content> were growth deficient according to their chronological age, with frequent abnormal bone mineralisation and vitamin D deficiency. Children requiring parenteral nutrition seven days a week had citrulline concentrations below 10 <jats:italic>\u03bc<\/jats:italic>mol\/L. Cholestasis was not seen.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.14260","type":"journal-article","created":{"date-parts":[[2018,2,6]],"date-time":"2018-02-06T11:14:51Z","timestamp":1517915691000},"page":"1088-1093","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Nutritional therapy complications in children with ultra\u2010short bowel syndrome include growth deficiency but not cholestasis"],"prefix":"10.1111","volume":"107","author":[{"given":"Katarzyna","family":"Olszewska","sequence":"first","affiliation":[{"name":"Department of Paediatrics, Nutrition and Metabolic Diseases The Children's Memorial Health Institute Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janusz","family":"Ksiazyk","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Nutrition and Metabolic Diseases The Children's Memorial Health Institute Warsaw 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