{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:08:07Z","timestamp":1790615287426,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Perinatal asphyxia is one of the most frequent causes of neonatal morbidity and mortality worldwide, and 96% of the burden of neonatal encephalopathy occurs in low\u2010income countries. This study investigated the feasibility of providing neuroprotective treatment for neonatal encephalopathy in low\u2010income countries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Neonates with a gestational age of at least 36\u00a0weeks, with signs of perinatal asphyxia, were included in this 2015 observational study in three hospitals in Kinshasa, capital of the Democratic Republic of Congo. Their characteristics were described, including the time to admission and Thompson score on admission.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We found that 42 of 134 patients (31.3%) reached the hospital within six hours of birth with a Thompson score of at least seven on admission. Another 15 patients (11.2%) had a five\u2010minute Apgar score of up to five, without a Thompson score, and were eligible for treatment. Of the 57 (42.5%) eligible patients, 31 were discharged (54.4%), 25 died (43.9%) and one (1.8%) remained in hospital at the end of the study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Interventional studies are feasible and necessary, especially in countries where the burden of neonatal encephalopathy is largest. A Thompson score of 7\u201315 might be a useful entry criterion for neuroprotective treatment in low\u2010income countries.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.14263","type":"journal-article","created":{"date-parts":[[2018,2,9]],"date-time":"2018-02-09T13:55:09Z","timestamp":1518184509000},"page":"1345-1349","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Observational study shows that it is feasible to provide neuroprotective treatment for neonatal encephalopathy in low\u2010income countries"],"prefix":"10.1111","volume":"107","author":[{"given":"T","family":"Biselele","sequence":"first","affiliation":[{"name":"Neonatal Unit Department of Pediatrics University Hospital of Kinshasa Kinshasa DR Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Bambi","sequence":"additional","affiliation":[{"name":"Neonatal Unit Department of Pediatrics University Hospital of Kinshasa Kinshasa 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