{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T11:09:26Z","timestamp":1750158566588},"reference-count":22,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,3,30]],"date-time":"2018-03-30T00:00:00Z","timestamp":1522368000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study described outcomes following treatment for lactose intolerance, which is common in children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The medical records of children aged 6\u201318\u00a0years who underwent lactose hydrogen breath testing at Dana\u2010Dwek Children's Hospital, Tel Aviv, Israel, from August 2012 to August 2014 were analysed. We compared 154 children with gastrointestinal symptoms and positive lactose hydrogen breath tests to 49 children with negative test results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 154 children in the study group, 89 (57.8%) were advised to follow a lactose\u2010restricted diet, 32 (20.8%) were advised to avoid lactose completely, 18 (11.7%) were instructed to use substitute enzymes, and 15 (9.7%) did not receive specific recommendations. Only 11 patients (7.1%) received recommendations to add calcium\u2010rich foods or calcium supplements to their diet. Lactose reintroduction was attempted in 119 of 154 patients (77.3%), and 65 of 154 (42.2%) experienced clinical relapses. At the final follow\u2010up of 3.3\u00a0years, 62.3% of the study children were still observing a restricted diet. Older children and those who were symptomatic during lactose hydrogen breath testing were more likely to be on a prolonged restricted diet.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our long\u2010term follow\u2010up of lactose\u2010intolerant children showed that only a third were able to achieve a regular diet.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.14305","type":"journal-article","created":{"date-parts":[[2018,3,5]],"date-time":"2018-03-05T15:46:40Z","timestamp":1520264800000},"page":"1389-1394","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["One\u2010third of children with lactose intolerance managed to achieve a regular diet at the three\u2010year follow\u2010up point"],"prefix":"10.1111","volume":"107","author":[{"given":"Anat","family":"Yerushalmy\u2010Feler","sequence":"first","affiliation":[{"name":"The Pediatric Gastroenterology Unit \u2018Dana\u2010Dwek\u2019 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