{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T21:48:00Z","timestamp":1781128080023,"version":"3.54.1"},"reference-count":21,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2018,4,17]],"date-time":"2018-04-17T00:00:00Z","timestamp":1523923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Department of Research and Development of Region Sk\u00e5ne"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>We studied the impact of maternal and pregnancy\u2010related conditions and the effect of gestational age itself, on the health of infants born late preterm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Singletons born in gestational weeks 34 + 0 to 41 + 6 in 1995\u20132013 in the southern region of Sweden were identified from a perinatal register. We found 14 030 infants born late preterm and 294 814 born at term. A hierarchical system was developed to examine the impact of pregnancy complications. The outcomes studied were as follows: neonatal death, central nervous system (<jats:styled-content style=\"fixed-case\">CNS<\/jats:styled-content>) or respiratory disease, infection, neonatal admission and respiratory support. Odds ratios (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>) and 95% confidence intervals (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>) were obtained using logistic regression analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Late preterm infants were at increased risk for all outcomes compared to term infants, with adjusted <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>s from 13.1 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 12.7\u201313.6) for neonatal admission to 2.3 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.8\u20132.9) for infections. Late preterm birth after preterm prelabour rupture of membranes was associated with an overall lower risk compared to late preterm births due to other causes. Exposure to antepartum haemorrhage or maternal diabetes increased the risk for <jats:styled-content style=\"fixed-case\">CNS<\/jats:styled-content> and respiratory morbidity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Morbidity decreased in late preterm infants with increasing gestational age. Underlying conditions accounted for a substantial part of the morbidity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.14321","type":"journal-article","created":{"date-parts":[[2018,3,25]],"date-time":"2018-03-25T13:44:17Z","timestamp":1521985457000},"page":"1521-1528","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Underlying maternal and pregnancy\u2010related conditions account for a substantial proportion of neonatal morbidity in late preterm infants"],"prefix":"10.1111","volume":"107","author":[{"given":"Anna","family":"Bonnevier","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Sk\u00e5ne University Hospital Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Brodszki","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Sk\u00e5ne University Hospital Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars J.","family":"Bj\u00f6rklund","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Neonatology Lund University Sk\u00e5ne University Hospital Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"K\u00e4ll\u00e9n","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Faculty of Medicine Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,4,17]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.7.843"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0706475"},{"key":"e_1_2_12_4_1","unstructured":"Official statistics of Sweden.Statistics on pregnancies deliveries and newborn infants 2016. 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