{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T05:25:01Z","timestamp":1783401901433,"version":"3.54.6"},"reference-count":33,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2018,4,26]],"date-time":"2018-04-26T00:00:00Z","timestamp":1524700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003745","name":"Stiftelserna Wilhelm och Martina Lundgrens","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003745","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008314","name":"LifeWatch \u2013 Niclas \u00d6berg Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008314","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study identified whether children who had screened positive for either developmental language disorder (<jats:styled-content style=\"fixed-case\">DLD<\/jats:styled-content>) or autism spectrum disorder (<jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>) at the age of 2.5 years had neurodevelopmental assessments five years later.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Our study cohort were 288 children born from 1 July 2008 to 20 June 2009 who screened positive for <jats:styled-content style=\"fixed-case\">DLD<\/jats:styled-content> and, or, <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content> at 2.5 years. Of these, 237 children were referred to, and assessed, at the Paediatric Speech and Language Pathology clinic (n = 176) or the Child Neuropsychiatry Clinic (n = 61) at the Queen Silvia Children's Hospital, Gothenburg, Sweden. Clinical registers covering all relevant outpatient clinics were reviewed five years later with regard to established diagnoses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>When the 237 were followed up five years later, 96 (40%) had established neurodevelopmental disorders or problems, often beyond <jats:styled-content style=\"fixed-case\">DLD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>. Co\u2010existing problems were common in this cohort and multidisciplinary assessments were indicated. The other 60% did not appear in subsequent clinic records. It is likely that this 40% was a minimum rate and that more children will be referred for developmental problems later.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Five years after they had been screened positive for <jats:styled-content style=\"fixed-case\">DLD<\/jats:styled-content> and, or autism at 2.5 years, 40% of our cohort had remaining or other developmental problems.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.14358","type":"journal-article","created":{"date-parts":[[2018,4,11]],"date-time":"2018-04-11T03:26:40Z","timestamp":1523417200000},"page":"1739-1749","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Development problems were common five years after positive screening for language disorders and, or, autism at 2.5 years of age"],"prefix":"10.1111","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7488-8482","authenticated-orcid":false,"given":"Carmela","family":"Miniscalco","sequence":"first","affiliation":[{"name":"Gillberg Neuropsychiatry Centre Institute of Neuroscience and Physiology University of Gothenburg Gothenburg Sweden"},{"name":"Department of Paediatric Speech and Language Pathology Queen Silvia Children's Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4516-7747","authenticated-orcid":false,"given":"Elisabeth","family":"Fernell","sequence":"additional","affiliation":[{"name":"Gillberg Neuropsychiatry Centre Institute of Neuroscience and Physiology University of Gothenburg Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy","family":"Thompson","sequence":"additional","affiliation":[{"name":"Gillberg Neuropsychiatry Centre Institute of Neuroscience and Physiology University of Gothenburg Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Sandberg","sequence":"additional","affiliation":[{"name":"Department of Paediatric Speech and Language Pathology Queen Silvia Children's Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"Kadesj\u00f6","sequence":"additional","affiliation":[{"name":"Gillberg Neuropsychiatry Centre Institute of Neuroscience and Physiology University of Gothenburg Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Gillberg","sequence":"additional","affiliation":[{"name":"Gillberg Neuropsychiatry Centre Institute of Neuroscience and Physiology University of Gothenburg Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,4,26]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0158753"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.12721"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-1467"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/13682820701546854"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2008.02034.x"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-13-206"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.12573"},{"key":"e_1_2_11_9_1","volume-title":"Language disorders from infancy through adolescence: listening, speaking, reading, writing, and communicating","author":"Paul R","year":"2012"},{"key":"e_1_2_11_10_1","unstructured":"ArvidssonT HolmbergL ReuterA Str\u00f6mbomA.Barnh\u00e4lsov\u00e5rdsrapport f\u00f6r verksamhets\u00e5r 2012 and 2013 [Annual Child Health Care Report statistics]. 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