{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T05:47:45Z","timestamp":1778824065748,"version":"3.51.4"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,7,13]],"date-time":"2018-07-13T00:00:00Z","timestamp":1531440000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study compiled percentiles for cardiorespiratory parameters in healthy term neonates during quiet sleep.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We enrolled 215 healthy term neonates born at Hannover Medical School, Germany, between October 2011 and March 2013. They were prospectively observed on the maternity ward at a median age of two days using six\u2010hour recordings of pulse oximeter plethysmography, oxygen saturation, thoracic breathing movements and electrocardiogram during sleep in a supine position. We examined their heart rate, respiratory rate and oxygen saturation during quiet sleep, plus bradycardias, apnoeas lasting at least four\u2010seconds and desaturations below 85%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The 3rd, 50th and 97th percentiles were calculated as follows: heart rate 87, 112 and 133 beats per minute, respiratory rate 32, 44 and 57 per minute and oxygen saturation 94, 98 and 100%. Desaturations, apnoeas and bradycardias below 80 beats per minute were common and recorded in 54%, 98% and 30% of participants. In contrast, only 7% experienced bradycardias of less than two\u2010thirds of the baseline heart rate and 5% experienced apnoeas exceeding 15 seconds.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our results will facilitate the evidence\u2010based valuation of cardiorespiratory parameters in term neonates and help validate the significance of cardiorespiratory events in preterm infants at discharge.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.14470","type":"journal-article","created":{"date-parts":[[2018,6,21]],"date-time":"2018-06-21T11:35:43Z","timestamp":1529580943000},"page":"231-238","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Heart rate, respiratory rate, apnoeas and peripheral arterial oxygen saturation in healthy term neonates during quiet sleep"],"prefix":"10.1111","volume":"108","author":[{"given":"B","family":"Bohnhorst","sequence":"first","affiliation":[{"name":"Department of Paediatric Pneumology, Allergology and Neonatology Hannover Medical School Hannover Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Seidel","sequence":"additional","affiliation":[{"name":"Medical Clinic 3 St. Bernward Hospital Hildesheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"B\u00f6hne","sequence":"additional","affiliation":[{"name":"Department of Paediatric Pneumology, Allergology and Neonatology Hannover Medical School Hannover Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Peter","sequence":"additional","affiliation":[{"name":"Department of Paediatric Pneumology, Allergology and Neonatology Hannover Medical School Hannover Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3624-6251","authenticated-orcid":false,"given":"S","family":"Pirr","sequence":"additional","affiliation":[{"name":"Department of Paediatric Pneumology, Allergology and Neonatology Hannover Medical School Hannover Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,7,13]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2010.03.004"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200005000-00050"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2013.07.016"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2015.164"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2015.165"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7211206"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2010.191437"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)80919-9"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2010.196758"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(99)70056-9"},{"key":"e_1_2_11_12_1","volume-title":"Nelson textbook of pediatrics","author":"Bernstein D","year":"2016"},{"key":"e_1_2_11_13_1","volume-title":"Neonatologie: Die Medizin des Fr\u00fch\u2010 und Reifgeborenen","author":"Robel\u2010Tillig E","year":"2010"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02083144"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)02162-2"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2005.03.015"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.5600"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.2012.03731.x"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/fn.87.3.F217"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2010.02097.x"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.76.3.333"},{"key":"e_1_2_11_22_1","unstructured":"PoetsC BohnhorstB RothB.Therapie idiopathischer Apnoen Bradykardien und Hypox\u00e4mien bei Fr\u00fchgeborenen.AWMF\u2010LeitlinieNr. 024\u2010013 April2014."},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.17.2199"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-2443"},{"key":"e_1_2_11_25_1","first-page":"341","article-title":"Arterial oxygen saturation and breathing movements during the first year of life","volume":"15","author":"Poets CF","year":"1991","journal-title":"J Dev Physiol"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/fn.83.1.F35"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedneo.2012.11.011"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1439-054x.2001.01148.x"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-0160"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.1950010409"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1088\/0967-3334\/24\/3\/304"}],"container-title":["Acta Paediatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fapa.14470","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apa.14470","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T07:31:56Z","timestamp":1694676716000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apa.14470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,13]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["10.1111\/apa.14470"],"URL":"https:\/\/doi.org\/10.1111\/apa.14470","archive":["Portico"],"relation":{},"ISSN":["0803-5253","1651-2227"],"issn-type":[{"value":"0803-5253","type":"print"},{"value":"1651-2227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,13]]},"assertion":[{"value":"2017-12-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}