{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T13:37:00Z","timestamp":1792157820208,"version":"4.4.0"},"reference-count":9,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,6,13]],"date-time":"2019-06-13T00:00:00Z","timestamp":1560384000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The optimal treatment for foetal supraventricular tachycardia (<jats:styled-content style=\"fixed-case\">SVT<\/jats:styled-content>) in twin pregnancies is unclear because of the possible impact on the second twin. This review compared a foetus we treated with antiarrhythmic drugs with the previous case studies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Our case was a dichorionic diamniotic twin pregnancy, where one twin developed foetal hydrops secondary to <jats:styled-content style=\"fixed-case\">SVT<\/jats:styled-content> at 22\u00a0weeks of gestation. We searched PubMed to look for previous cases of <jats:styled-content style=\"fixed-case\">SVT<\/jats:styled-content> in twin pregnancies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Treatment with transplacental antiarrhythmic therapy from 22 to 36\u00a0weeks of gestation successfully resolved the <jats:styled-content style=\"fixed-case\">SVT<\/jats:styled-content> in our affected twin without any impact on the healthy twin or mother. We only found seven similar cases of <jats:styled-content style=\"fixed-case\">SVT<\/jats:styled-content> in twin pregnancies from 1999 to 2017. Although there was no consensus on the treatment that should be provided, none of the studies reported side effects in the twins or the mothers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Despite a lack of data on <jats:styled-content style=\"fixed-case\">SVT<\/jats:styled-content> in twin pregnancies, our case, and the previous cases we identified, allowed us to conclude that transplacental antiarrhythmic treatment can successfully achieve cardioversion in the affected twin. It can do this without side effects for the healthy foetus or the mother, even if the treatment lasts for a long period of time.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.14870","type":"journal-article","created":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T14:48:08Z","timestamp":1558536488000},"page":"1580-1583","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Is antiarrhythmic therapy safe in twin pregnancies?"],"prefix":"10.1111","volume":"108","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6729-171X","authenticated-orcid":false,"given":"Valentina","family":"Gesuete","sequence":"first","affiliation":[{"name":"Cardiology Service Institute for Maternal and Child Health IRCCS Burlo Garofolo Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilaria","family":"Fantasia","sequence":"additional","affiliation":[{"name":"Unit of Fetal Medicine and Prenatal Diagnosis Institute for Maternal and Child Health IRCCS Burlo Garofolo Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Lo Bello","sequence":"additional","affiliation":[{"name":"Unit of Fetal Medicine and Prenatal Diagnosis Institute for Maternal and Child Health IRCCS Burlo Garofolo Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Rizzante","sequence":"additional","affiliation":[{"name":"Unit of Fetal Medicine and Prenatal Diagnosis Institute for Maternal and Child Health IRCCS Burlo Garofolo Trieste Italy"},{"name":"Department Of Medical Surgical and Health Science University of Trieste Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biancamaria","family":"D'Agata Mottolese","sequence":"additional","affiliation":[{"name":"Cardiology Service Institute for Maternal and Child Health IRCCS Burlo Garofolo Trieste 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