{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:38:21Z","timestamp":1792726701406,"version":"4.5.0"},"reference-count":39,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T00:00:00Z","timestamp":1570060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006310","name":"Medicinska Forskningsr\u00e5det","doi-asserted-by":"publisher","award":["#2016\u201001131"],"award-info":[{"award-number":["#2016\u201001131"]}],"id":[{"id":"10.13039\/501100006310","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Studies indicate that reduced foetal haemoglobin levels are related to increased neonatal morbidity rates. This study investigated the relationships between sampling\u2010related blood loss and adult blood transfusions administered during postnatal days 1\u201014 and the development of severe neonatal morbidities in extremely preterm infants born before 28\u00a0weeks of gestation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The medical files of 149 extremely preterm infants born at two university hospitals in Sweden from 2013 to 2018 were investigated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Blood sampling resulted in a 58% depletion of the endogenous blood volume postnatal days 1\u201014 (median 40.4\u00a0mL\/kg, interquartile range 23.9\u201053.3\u00a0mL\/kg) and correlated with the adult erythrocyte transfusion volume (r\n                      <jats:sub>S<\/jats:sub>\n                      \u00a0=\u00a00.870,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001). Sampling\u2010related blood loss on postnatal days 1\u20107, adjusted for gestational age at birth and birth weight standard deviation score, was associated with the development of bronchopulmonary dysplasia (BPD) (odds ratio by a 10\u2010unit increase 2.4, 95% confidence interval 1.1\u20105.4) (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.03). No associations were found between blood sampling and intraventricular haemorrhage or necrotising enterocolitis in the full statistical model. The largest proportion of sampling\u2010related blood was used for blood gas analyses (48.7%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Diagnostic blood sampling led to major endogenous blood loss replaced with adult blood components and was associated with the development of BPD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.15003","type":"journal-article","created":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T13:08:16Z","timestamp":1568120896000},"page":"679-687","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Neonatal clinical blood sampling led to major blood loss and was associated with bronchopulmonary dysplasia"],"prefix":"10.1111","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6669-260X","authenticated-orcid":false,"given":"William","family":"Hellstr\u00f6m","sequence":"first","affiliation":[{"name":"Department of Paediatrics Institute of Clinical Sciences Sahlgrenska Academy University of Gothenburg Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linn\u00e9a","family":"Forssell","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Lund Paediatrics Lund University Sk\u00e5ne University Hospital Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Morsing","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Lund Paediatrics Lund University Sk\u00e5ne University Hospital Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"S\u00e4vman","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Institute of Clinical Sciences Sahlgrenska Academy University of Gothenburg Gothenburg Sweden"},{"name":"Region V\u00e4stra G\u00f6taland Department of Neonatology The Queen Silvia Children's Hospital Sahlgrenska University Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Ley","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Lund Paediatrics Lund University Sk\u00e5ne University Hospital Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,10,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2016-1821"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1084-2756(99)80003-7"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2012.04.003"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/neo.9-11-e520"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.12.1499"},{"key":"e_1_2_10_7_1","volume-title":"Transfusion\u2010related decrease in fetal hemoglobin \u2010 a strong predictor of severe mobility in very preterm infants","author":"Martinsson T","year":"2018"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/10409239509085142"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-017-2665-z"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.13350"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/1994\/83780"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V59.5.976.976"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.13979.1"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365510050184949"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-1680"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-1773"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00445764"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(78)80282-0"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/heapol\/czs053"},{"issue":"2","key":"e_1_2_10_20_1","first-page":"100","article-title":"Premature delivery and the millennium development goal","volume":"5","author":"Nour NM","year":"2012","journal-title":"Rev Obstet Gynecol"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.2021"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.1204"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep22717"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00496419"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0138680"},{"key":"e_1_2_10_26_1","unstructured":"Swedish Neonatal Quality Register (SNQ).SNQ:s \u00e5rsrapport: neonatalv\u00e5rdens omfattning och resultat \u00e5r 2017.2017. 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