{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T21:11:42Z","timestamp":1785359502248,"version":"3.55.0"},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,11,10]],"date-time":"2019-11-10T00:00:00Z","timestamp":1573344000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess changes in skin conductance during retinopathy of prematurity screening and to study the correlation between the skin conductance and a validated pain scale.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Prospective observational study. Fifty\u2010three eye examinations were performed in 32 preterm infant candidates for retinopathy of prematurity screening. Outcome measures were changes in Premature Infant Pain Profile\u2010Revised (PIPP\u2010R) scale and number of skin conductance fluctuations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was a significant increase from baseline in the number of skin conductance fluctuations and PIPP\u2010R during the procedure. The maximum value of number of skin conductance fluctuations was 0.64\u00a0\u00b1\u00a00.44 peaks\/sec, and the maximum value of PIPP\u2010R was 10.8\u00a0\u00b1\u00a03.3.<\/jats:p><jats:p>A correlation between the skin conductance and PIPP\u2010R was not found at any time during the eye examination. Repeated measures correlation analyses showed only a moderate positive correlation between PIPP\u2010R and number of skin conductance fluctuation values.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There were significant changes in both PIPP\u2010R and number of skin conductance fluctuations during retinopathy of prematurity screening, reaffirming that this procedure is painful and stressful. The number of skin conductance fluctuations and PIPP\u2010R are not significantly correlated, which likely reflects that these parameters evaluate different but complementary aspects of neonatal pain responses.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.15066","type":"journal-article","created":{"date-parts":[[2019,10,20]],"date-time":"2019-10-20T13:59:51Z","timestamp":1571579991000},"page":"935-942","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Pain assessment during eye examination for retinopathy of prematurity screening: Skin conductance versus PIPP\u2010R"],"prefix":"10.1111","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5541-6968","authenticated-orcid":false,"given":"Alejandro","family":"Avila\u2010Alvarez","sequence":"first","affiliation":[{"name":"Department of Neonatology Complexo Hospitalario Universitario de A Coru\u00f1a A Coru\u00f1a Spain"},{"name":"A Coru\u00f1a Biomedical 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