{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T07:12:31Z","timestamp":1760080351246,"version":"3.37.3"},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,12,25]],"date-time":"2019-12-25T00:00:00Z","timestamp":1577232000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI14\/01568"],"award-info":[{"award-number":["PI14\/01568"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>We aim to assess oculomotor behaviour in children adopted from Eastern Europe, who are at high risk of maternal alcohol consumption.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross\u2010sectional study included 29 adoptees and 29 age\u2010matched controls. All of them underwent a complete ophthalmological examination. Oculomotor control, including fixation and saccadic performance, was assessed using a DIVE device, with eye tracking technology. Anthropometric and facial measurements were obtained from all the adopted children, to identify features of foetal alcohol spectrum disorders (FASD). Fixational and saccadic outcomes were compared between groups, and the effect of adoption and FASD features quantified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Oculomotor performance was poorer in adopted children. They presented shorter (0.53 vs 1.43 milliseconds in the long task and 0.43 vs 0.82 in the short task) and more unstable fixations (with a bivariate contour ellipse area of 27.9 vs 11.6 degree<jats:sup>2<\/jats:sup> during the long task and 6.9 vs 1.3 degree<jats:sup>2<\/jats:sup> during the short task) and slower saccadic reactions (278 vs 197 milliseconds). Children with sentinel finding for FASD showed the worst oculomotor outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Children adopted from Eastern Europe present oculomotor deficits, affecting both fixation and saccadic skills. We highlight prenatal exposure to alcohol as the main cause for these deficits.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.15135","type":"journal-article","created":{"date-parts":[[2019,12,12]],"date-time":"2019-12-12T10:05:30Z","timestamp":1576145130000},"page":"1439-1444","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Oculomotor deficits in children adopted from Eastern Europe"],"prefix":"10.1111","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1777-0349","authenticated-orcid":false,"given":"Victoria","family":"Pueyo","sequence":"first","affiliation":[{"name":"Ophthalmology Department Aragon Institute for Health Research (IIS Arag\u00f3n) Miguel Servet University Hospital Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7314-5388","authenticated-orcid":false,"given":"Olimpia","family":"Castillo","sequence":"additional","affiliation":[{"name":"Ophthalmology Department Aragon Institute for Health Research (IIS Arag\u00f3n) Miguel Servet University Hospital Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inmaculada","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Ophthalmology Department Aragon Institute for Health Research (IIS Arag\u00f3n) Miguel Servet University Hospital Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Ortin","sequence":"additional","affiliation":[{"name":"Aragon Institute for Health Research (IIS Arag\u00f3n) I3A Institute for Research in Engineering Universidad de Zaragoza Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Perez","sequence":"additional","affiliation":[{"name":"Ophthalmology Department Aragon Institute for Health Research (IIS Arag\u00f3n) Miguel Servet University Hospital Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Gutierrez","sequence":"additional","affiliation":[{"name":"Aragon Institute for Health Research (IIS Arag\u00f3n) I3A Institute for Research in Engineering Universidad de Zaragoza Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther","family":"Prieto","sequence":"additional","affiliation":[{"name":"Ophthalmology Department Aragon Institute for Health Research (IIS Arag\u00f3n) Miguel Servet University Hospital Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian","family":"Alejandre","sequence":"additional","affiliation":[{"name":"I3A Institute for Research in Engineering Universidad de Zaragoza Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Belen","family":"Masia","sequence":"additional","affiliation":[{"name":"Aragon Institute for Health Research (IIS Arag\u00f3n) I3A Institute for Research in Engineering Universidad de Zaragoza Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,12,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-0066"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-0712"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.2008.01430.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0376-8716(87)90087-1"},{"key":"e_1_2_9_6_1","first-page":"1","article-title":"Fetal alcohol syndrome. 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