{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T17:54:37Z","timestamp":1793728477508,"version":"4.6.1"},"reference-count":30,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,4,19]],"date-time":"2020-04-19T00:00:00Z","timestamp":1587254400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009123","name":"Norges Teknisk-Naturvitenskapelige Universitet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009123","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Neonatal jaundice is an important cause of morbidity and mortality, and identifying the condition remains a challenge. This study evaluated a novel method of estimating bilirubin levels from colour\u2010calibrated smartphone images.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional prospective study was undertaken at two hospitals in Norway from February 2017 to March 2019, with standardised illumination at one hospital and non\u2010standardised illumination at the other hospital. Healthy term\u2010born infants with a normal birthweight were recruited up to 15\u00a0days of age. The main outcome measures were bilirubin estimates from digital images, plus total bilirubin in serum (TSB) and transcutaneous bilirubin (TcB).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Bilirubin estimates were performed for 302 newborn infants, and 76 had severe jaundice. The correlation between the smartphone estimates and TSB was measured by Pearson's\n                      <jats:italic>r<\/jats:italic>\n                      and was .84 for the whole sample. The correlation between the image estimates and TcB was 0.81. There were no significant differences between the hospitals. Sensitivity was 100%, and specificity was 69% for identifying severe jaundice of more than 250\u00a0\u00b5mol\/L.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A smartphone\u2010based tool that estimated bilirubin levels from digital images identified severe jaundice with high sensitivity and could provide a screening tool for neonatal jaundice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.15287","type":"journal-article","created":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T08:48:21Z","timestamp":1586335701000},"page":"2532-2538","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["Bilirubin estimates from smartphone images of newborn infants\u2019 skin correlated highly to serum bilirubin levels"],"prefix":"10.1111","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6757-7398","authenticated-orcid":false,"given":"Anders","family":"Aune","sequence":"first","affiliation":[{"name":"Department of Public Health and Nursing Norwegian University of Science and Technology Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunnar","family":"Vartdal","sequence":"additional","affiliation":[{"name":"Picterus AS Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e5kon","family":"Bergseng","sequence":"additional","affiliation":[{"name":"Department of Pediatrics St. Olav University Hospital Trondheim Norway"},{"name":"Department of Laboratory Medicine Children\u2019s and Women\u2019s Health Norwegian University of Science and Technology Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2608-3759","authenticated-orcid":false,"given":"Lise Lyngsnes","family":"Randeberg","sequence":"additional","affiliation":[{"name":"Department of Electronic Systems Norwegian University of Science and Technology Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8311-4956","authenticated-orcid":false,"given":"Elisabeth","family":"Darj","sequence":"additional","affiliation":[{"name":"Department of Public Health and Nursing Norwegian University of Science and Technology Trondheim Norway"},{"name":"Department of Obstetrics and Gynecology St. Olav University Hospital Trondheim Norway"},{"name":"Department of Women\u2019 and Children\u2019s Health Uppsala University Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,4,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2016-311556"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1986.tb10242.x"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2013.208"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2013-305506"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2011.02.014"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2008.09.106"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2014.05.009"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2008.150714"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2007.11.003"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0154664"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.10.001250"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10916-016-0523-4"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0197938"},{"key":"e_1_2_11_15_1","first-page":"597","article-title":"Evaluation of an automatic image\u2010based screening technique for neonatal hyperbilirubinemia","volume":"54","author":"Rong ZH","year":"2016","journal-title":"Zhonghua Er Ke Za Zhi"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2017-0312"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.18203\/2349-3291.ijcp20175928"},{"key":"e_1_2_11_18_1","unstructured":"VartdalG Randeberg LiseL AuneA KringstadA PicterusASImage Based Bilirubin Determination. 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