{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T04:58:01Z","timestamp":1782277081844,"version":"3.54.5"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T00:00:00Z","timestamp":1603238400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2009\u20101093"],"award-info":[{"award-number":["2009\u20101093"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2016\u201003109"],"award-info":[{"award-number":["2016\u201003109"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of the study was to investigate cognitive outcomes at 6.5\u00a0years in children born very preterm, in relation to neonatal characteristics and 2.5\u2010year neurodevelopment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective cohort, with gestational age 22.3\u201031.9\u00a0weeks, born 2004\u20102007, were examined at 2.5\u00a0years with the Bayley Scales of Infant and Toddler Development (Bayley\u2010III) (n\u00a0=\u00a0100) and at 6.5\u00a0years with the Wechsler Intelligence Scales (n\u00a0=\u00a091).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Neonatal factors independently related to 6.5\u2010year outcome were gestational age, retinopathy of prematurity and treated persistent ductus arteriosus. The Bayley\u2010III cognitive scores explained only 44% of the Full\u2010Scale Intelligence Quotient result at 6.5\u00a0years, and 22% of the children had Wechsler index results below \u22121 SD, indicating cognitive impairment, after average test results at 2.5\u00a0years. The relative risk to score below \u22121 SD on the Full\u2010Scale IQ was 2.83 (95% CI 1.45\u20105.53) in children with gestational age below 28\u00a0weeks and 2.22 (95% CI 1.18\u20104.17) at gestational age 28\u201031\u00a0weeks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Very preterm infants born in the 2000s had increased risks for impaired cognition at 6.5\u00a0years, but individual predictions based on neonatal risks and 2.5\u2010year test results were not enough to identify all high\u2010risk children.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.15586","type":"journal-article","created":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T08:59:30Z","timestamp":1600419570000},"page":"846-854","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Average 2.5\u2010year neurodevelopmental test results in children born very preterm did not rule out cognitive deficits at 6.5 years of age"],"prefix":"10.1111","volume":"110","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8493-3788","authenticated-orcid":false,"given":"Ylva F.","family":"Kaul","sequence":"first","affiliation":[{"name":"Department of Women\u2019s and Children\u2019s Health Uppsala University Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nima","family":"Naseh","sequence":"additional","affiliation":[{"name":"Department of Women\u2019s and Children\u2019s Health Uppsala University Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarina","family":"Strand Brodd","sequence":"additional","affiliation":[{"name":"Department of Women\u2019s and Children\u2019s Health Uppsala University Uppsala Sweden"},{"name":"Centre for Clinical Research S\u00f6rmland Uppsala University Uppsala 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