{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:40:47Z","timestamp":1747183247525,"version":"3.40.5"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,2,28]],"date-time":"2021-02-28T00:00:00Z","timestamp":1614470400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess cerebral oxygenation in premature infants who are transitioning from nasal continuous positive airway pressure (nCPAP) to heated humidified high\u2010flow nasal cannula therapy (HFNC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective observational study done in a single\u2010centre neonatal intensive care unit (NICU). Regional cerebral oxygen saturations (RcSO<jats:sub>2<\/jats:sub>) were measured using frequency\u2010domain near\u2010infrared spectroscopy (FD\u2010NIRS) in very low birthweight (VLBW) premature infants born at &lt;32\u00a0weeks transitioning from nCPAP to HFNC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Median gestational age was 27\u00a0weeks and median birthweight was 924\u00a0g. Recordings were performed at a median gestational age of 30\u00a0weeks and a median postnatal age of 10\u00a0days. Median weight at study entry was 1111\u00a0g. Cerebral oxygenation was not significantly different in infants transitioning from nCPAP to HFNC (66% vs 66%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>No difference in cerebral oxygenation in premature infants transitioning from nCPAP to HFNC was observed. This finding is reassuring and further supports the use of HFNC in preterm infants.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.15811","type":"journal-article","created":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T03:57:03Z","timestamp":1613620623000},"page":"2059-2064","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cerebral oxygenation is stable in preterm infants transitioning to heated humidified high\u2010flow nasal cannula therapy"],"prefix":"10.1111","volume":"110","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7075-5829","authenticated-orcid":false,"given":"Arun","family":"Sett","sequence":"first","affiliation":[{"name":"Department of Paediatrics Mercy Hospital for Women Heidelberg Vic Australia"},{"name":"Joan Kirner Women\u2019s and Children\u2019s Hospital Western Health St Alban\u2019s Vic. 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