{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:55:06Z","timestamp":1790398506264,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,7,27]],"date-time":"2021-07-27T00:00:00Z","timestamp":1627344000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of the study was to describe age\u2010 and sex\u2010specific prevalence of serious bacterial infections (SBI: urinary tract infection, bacteraemia, meningitis) among febrile infants \u226460\u00a0days in Sweden.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective study in 4 Pediatric Emergency Departments from 2014 to 2017, in previously healthy, full\u2010term infants \u226460\u00a0days with fever without a source.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 1,701 included infants, 214 (12.6%; 95% CI, 11.1\u201314.3) had an SBI. Urinary tract infection (UTI) was diagnosed in 196 (11.5%; 95% CI, 10.0\u201313.1) patients. In the \u226428 and 29\u201360\u00a0days age\u2010groups, meningitis prevalence was 0.9% (95% CI, 0.3\u20132.0) and 0.3% (95% CI, 0.1\u20130.8), whereas bacteraemia prevalence was 3.2% (95% CI, 1.9\u20134.9) and 0.6% (95% CI, 0.2\u20131.3). The SBI prevalence was higher in boys 16.0% (95% CI, 13.8\u201318.5) than girls 8.0% (95% CI, 6.2\u201310.2; <jats:italic>p<\/jats:italic>&lt;0.001), due to 2\u2010fold higher UTI risk. The prevalence of meningitis in boys was 0.3% (95% CI, 0.1\u2013 0.9) vs. 0.7% (95% CI, 0.2\u20131.6) in girls and of bacteraemia 1.8% (95% CI, 1.0\u20132.8) vs. 1.0% (95% CI, 0.4\u20132.0), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The total SBI prevalence was 12.6%, and UTI represented the vast majority. The prevalence of bacteraemia and meningitis was low, particularly in the 29\u201360\u00a0days age group, without significant difference between boys and girls.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.16043","type":"journal-article","created":{"date-parts":[[2021,7,26]],"date-time":"2021-07-26T17:41:10Z","timestamp":1627321270000},"page":"3069-3076","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Age\u2010 and sex\u2010specific prevalence of serious bacterial infections in febrile infants \u226460 days, in Sweden"],"prefix":"10.1111","volume":"110","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0466-4499","authenticated-orcid":false,"given":"Ioannis","family":"Orfanos","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences Lund University Lund Sweden"},{"name":"Department of Pediatrics Sk\u00e5ne University Hospital Lund 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