{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T02:19:05Z","timestamp":1789006745174,"version":"build-2803163510"},"reference-count":41,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2021,9,12]],"date-time":"2021-09-12T00:00:00Z","timestamp":1631404800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to determine clinician opinion regarding oxygen management in moderate\u2010late preterm resuscitation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An anonymous online questionnaire was distributed through email\/social messaging platforms to neonatologists in 21 countries (October 2020\u2010March 2021) via REDCap.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 695 respondents, 69% had access to oxygen blenders and 90% had pulse oximeters. Respondents from high\u2010income countries were more likely to have oxygen blenders than those from middle\u2010income countries (72% vs. 66%). Most initiated respiratory support with FiO<jats:sub>2<\/jats:sub> 0.21 (43%) or 0.3 (36%) but only 45% titrated FiO<jats:sub>2<\/jats:sub> to target SpO<jats:sub>2<\/jats:sub>. Most (89%) considered heart rate as a more important indicator of response than SpO<jats:sub>2<\/jats:sub>. Almost all (96%) supported the need for well\u2010designed trials to examine oxygenation in moderate\u2010late preterm resuscitation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Most clinicians resuscitated moderate\u2010late preterm infants with lower initial FiO<jats:sub>2<\/jats:sub> but some cannot\/will not target SpO<jats:sub>2<\/jats:sub> or titrate FiO<jats:sub>2<\/jats:sub>. Most consider heart rate as a more important indicator of infant response than SpO<jats:sub>2<\/jats:sub>.Large and robust clinical trials examining oxygen use for moderate\u2010late preterm resuscitation, including long\u2010term neurodevelopmental outcomes, are supported amongst clinicians.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.16091","type":"journal-article","created":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T17:16:27Z","timestamp":1630602987000},"page":"3261-3268","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Oxygen for the delivery room respiratory support of moderate\u2010to\u2010late preterm infants. An international survey of clinical practice from 21 countries"],"prefix":"10.1111","volume":"110","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5845-5647","authenticated-orcid":false,"given":"James X.","family":"Sotiropoulos","sequence":"first","affiliation":[{"name":"Faculty of Medicine School of Women\u2019s and Children\u2019s Health University of New South Wales Sydney NSW Australia"},{"name":"Department of Newborn Care The Royal Hospital for Women Randwick NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishal","family":"Kapadia","sequence":"additional","affiliation":[{"name":"Department of Pediatrics U.T. Southwestern Medical Center Dallas TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0061-4742","authenticated-orcid":false,"given":"Maximo","family":"Vento","sequence":"additional","affiliation":[{"name":"Health Research Institute La Fe Valencia Spain"},{"name":"University and Polytechnic Hospital La Fe Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yacov","family":"Rabi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Alberta Children's Hospital Research Institute University of Calgary Calgary AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ola D.","family":"Saugstad","sequence":"additional","affiliation":[{"name":"Northwestern University Chicago USA"},{"name":"University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Kishore","family":"Kumar","sequence":"additional","affiliation":[{"name":"Cloudnine Hospitals Jayanagar Bengaluru India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg M.","family":"Schm\u00f6lzer","sequence":"additional","affiliation":[{"name":"Centre for the Studies of Asphyxia and Resuscitation Neonatal Research Unit Royal Alexandra Hospital Edmonton AB Canada"},{"name":"Department of Pediatrics University of Alberta Edmonton AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huyan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Division of Neonatology Department of Pediatrics Children's Hospital of Philadelphia Philadelphia and University of Pennsylvania Perelman School of Medicine Philadelphia PA USA"},{"name":"Guangzhou Women and Children\u2019s Medical Center Tianhe District Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Yuan","sequence":"additional","affiliation":[{"name":"Guangzhou Women and Children\u2019s Medical Center Tianhe District Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gina","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Ulsan University Hospital Ulsan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5318-8877","authenticated-orcid":false,"given":"Satoshi","family":"Kusuda","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine Kyorin University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Arimitsu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Keio University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tinh Thu","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Medicine and Pharmacy at Ho Chi Minh City Ho Chi Minh City Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ratchada","family":"Kitsommart","sequence":"additional","affiliation":[{"name":"Division of Neonatology Department of Pediatrics Faculty of Medicine Siriraj Hospital Mahidol University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kee Thai","family":"Yeo","sequence":"additional","affiliation":[{"name":"Department of Neonatology KK Women\u2019s and Children\u2019s Hospital Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju Lee","family":"Oei","sequence":"additional","affiliation":[{"name":"Faculty of Medicine School of Women\u2019s and Children\u2019s Health University of New South Wales Sydney NSW Australia"},{"name":"Department of Newborn Care The Royal Hospital for Women Randwick NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,9,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000151761"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.107.4.642"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/sper.2002.37312"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-200004000-00018"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-200106000-00020"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-200106000-00017"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2005.03.008"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2018.07.009"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-0206"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-2972B"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)17189-4"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2006.06.134"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1159\/000143397"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-1510"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2006.12.015"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.13485"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2016-1452"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcped.2021.03.010"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(18)30451-0"},{"issue":"16","key":"e_1_2_10_21_1","first-page":"S185","article-title":"Neonatal life support: 2020 International consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations","volume":"142","author":"Wyckoff Myra H","year":"2020","journal-title":"Circulation"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-021-06737-1"},{"key":"e_1_2_10_24_1","unstructured":"The World Bank. World Bank Country and Lending Groups 2020. Available from:https:\/\/datahelpdesk.worldbank.org\/knowledgebase\/articles\/906519\u2010world\u2010bank\u2010country\u2010and\u2010lending\u2010groups. Accessed 6 April 2021."},{"key":"e_1_2_10_25_1","unstructured":"NCPR: Neonatal Cardiopulmonary Resuscitation Online: Japan Resuscitation Council (JRC)2015. Available from:http:\/\/www.ncpr.jp\/eng\/doc\/Textbook_of_NCPR.pdfAccessed 6 April 2021."},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60820-4"},{"key":"e_1_2_10_27_1","unstructured":"Anjue Medical Equipment Co. Ltd.Air\u2010oxygen blender. Available from:https:\/\/aj\u2010medical.en.alibaba.com\/product\/60765514379\u20100\/Air_Oxygen_Blender.html. Acessed 26 May 2021."},{"key":"e_1_2_10_28_1","unstructured":"Medical Device Depot Inc. Masimo Rad\u2010G Handheld Pulse Oximeter. Available from:https:\/\/www.medicaldevicedepot.com\/Masimo\u2010Rad\u2010G\u2010Handheld\u2010Pulse\u2010Oximeter\u2010p\/9847\u2010masimo.htm. Accessed 26 May 2021."},{"key":"e_1_2_10_29_1","unstructured":"The World Bank. GNI per capita Atlas Method ($US) 2019. Available from:https:\/\/data.worldbank.org\/indicator\/NY.GNP.PCAP.CD. Accessed 6 April 2021."},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/ped.13184"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2009.166462"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2017-314366"},{"key":"e_1_2_10_33_1","unstructured":"KapadiaV OeiJ SaugstadO RabiY FinerN Tarnow\u2010MordiW et al.BradyPrem study: heart rate is the most vital sign during resuscitation of preterms. EPAS\u20102018:4650.4."},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41372-019-0491-x"},{"key":"e_1_2_10_35_1","volume-title":"Meta\u2010analysis of neurodevelopmental outcomes after randomization of preterm infants to resuscitation with lower (FiO2 < 0.3) or higher (FiO2 > 0.6) oxygen strategies \u2010 are boys and girls equal? Proceeds of the Pediatrics Academic Societies Meeting","author":"Oei JL","year":"2018"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200412-1740OC"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-011643"},{"issue":"1","key":"e_1_2_10_38_1","article-title":"Effect of early versus delayed cord clamping in neonate on heart rate, breathing and oxygen saturation during first 10 minutes of birth \u2010 randomized clinical trial","volume":"7","author":"Kc A","year":"2019","journal-title":"Mat Health Neonat Perinatol"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2020.07.045"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1159\/000492712"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2016.01.002"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.7269"}],"container-title":["Acta Paediatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apa.16091","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/apa.16091","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apa.16091","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T09:36:49Z","timestamp":1692956209000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apa.16091"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,12]]},"references-count":41,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10.1111\/apa.16091"],"URL":"https:\/\/doi.org\/10.1111\/apa.16091","archive":["Portico"],"relation":{},"ISSN":["0803-5253","1651-2227"],"issn-type":[{"value":"0803-5253","type":"print"},{"value":"1651-2227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,12]]},"assertion":[{"value":"2021-05-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-31","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}