{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T12:05:53Z","timestamp":1772280353846,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,5,11]],"date-time":"2022-05-11T00:00:00Z","timestamp":1652227200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Bacterial meningitis (BM) is a common cause of hearing loss in childhood. Our aim was to investigate bacterial aetiology, hearing impairment and outcome in childhood BM with <jats:italic>vs<\/jats:italic>. without otitis media (OM) in Angola.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Hearing was tested by auditory brainstem response in 391 (76%) children with confirmed BM. The bacteria identified from the ear discharge were compared to those from cerebrospinal fluid (CSF). The hearing findings were compared among children with <jats:italic>vs<\/jats:italic>. without OM on days 1 and 7 of hospitalization, and at follow\u2010ups of 1, 3 and 6\u00a0month(s).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No correlation was found in bacteriology between the ear discharge and CSF. On day 7 in hospital, hearing impairment (&gt;40\u00a0dB) was common, regardless of whether concomitant OM or not (in 27% <jats:italic>vs<\/jats:italic>. 30%, respectively). Any hearing deficit on day 7 was associated with a higher risk of complicated or fatal clinical course (OR 2.76, CI<jats:sub>95%<\/jats:sub> 1.43\u20135.29, <jats:italic>p<\/jats:italic>\u00a0=\u00a0<jats:italic>0<\/jats:italic>.<jats:italic>002<\/jats:italic>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>No significant difference prevailed in hearing thresholds between children with or without OM in hospital on day 7 or at later follow\u2010ups. Any hearing impairment during hospital stay associated with a higher risk for complicated clinical course or death.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.16383","type":"journal-article","created":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T19:18:57Z","timestamp":1651519137000},"page":"1585-1593","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Hearing impairment in Angolan children with acute bacterial meningitis with and without otitis media"],"prefix":"10.1111","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8568-1997","authenticated-orcid":false,"given":"Laura","family":"Lempinen","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery University of Helsinki and Helsinki University Hospital  Helsinki 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