{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T00:14:11Z","timestamp":1768263251569,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,12,30]],"date-time":"2022-12-30T00:00:00Z","timestamp":1672358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>We evaluated antibiotic prescriptions issued for Finnish children with acute sinusitis by a nationwide private outpatient clinic network from 2014\u20132020. Data were compared before and after updated guidelines in 2018.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study comprised data on 45\u2009296 children aged 2\u201317\u2009years with acute sinusitis, namely diagnoses, ages, dates, the doctor's specialty and any antibiotics. We measured compliance with the updated 2018 Finnish guidelines, which recommended amoxicillin or amoxicillin\u2010clavulanic acid for children under 12\u2009years old, with doxycycline as an alternative for 12\u2009years plus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 6621\u20137585 visits per year for acute sinusitis in 2014\u20132019 and 2954 in 2020. Antibiotics were prescribed for 37.9%\u201341.6% of patients during the study years. Amoxicillin, including penicillin, accounted for 35.9% of prescriptions, followed by amoxicillin\u2010clavulanic acid (26.9%). Macrolides accounted for 20.6% and, encouragingly, decreased by 38% from 2014\u20132019. Doxycycline accounted for 5.3%. Paediatricians, general practitioners (GPs) and ear, nose and throat specialists followed the guidelines in 75.1%, 73.8% and 66.7% of cases, respectively. GPs prescribed antibiotics more often than other physicians.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Antibiotics were prescribed for about 40% of acute sinusitis visits by Finnish children from 2014\u20132019. Specialities differed with regard to prescribing rates and whether they followed the guidelines.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.16641","type":"journal-article","created":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T09:43:56Z","timestamp":1671788636000},"page":"1041-1048","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Antibiotic prescriptions for child sinusitis varied between specialties after Finnish guidelines were updated in 2018"],"prefix":"10.1111","volume":"112","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8153-1919","authenticated-orcid":false,"given":"Matti","family":"Korppi","sequence":"first","affiliation":[{"name":"Centre for Child, Adolescent, and Maternal Health Research Tampere University Hospital and Tampere University, Faculty of Medicine and Health Technology  Tampere Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3270-7660","authenticated-orcid":false,"given":"Sauli","family":"Palmu","sequence":"additional","affiliation":[{"name":"Centre for Child, Adolescent, and Maternal Health Research Tampere University Hospital and Tampere University, Faculty of Medicine and Health Technology  Tampere Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5989-8615","authenticated-orcid":false,"given":"Paula","family":"Heikkil\u00e4","sequence":"additional","affiliation":[{"name":"Centre for Child, Adolescent, and Maternal Health Research Tampere University Hospital and Tampere University, Faculty of Medicine and Health Technology  Tampere Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0819-7875","authenticated-orcid":false,"given":"P\u00e9ter","family":"Csonka","sequence":"additional","affiliation":[{"name":"Centre for Child, Adolescent, and Maternal Health Research Tampere University Hospital and Tampere University, Faculty of Medicine and Health Technology  Tampere Finland"},{"name":"Terveystalo Healthcare  Tampere Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,12,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365540410020857"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2021.110786"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-1071"},{"key":"e_1_2_10_5_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7573\/dic.2020-9-3","article-title":"Acute bacterial sinusitis in children: an updated review","volume":"9","author":"Leung AK","year":"2021","journal-title":"Drugs Context"},{"key":"e_1_2_10_6_1","unstructured":"Current Care Guidelines. Working group set up by the Finnish Medical Society Duodecim and the Finnish Association of Otorhinolaryngology \u2013 Head and Neck Surgery. Helsinki: The Finnish Medical Society Duodecim.Sinusitis.2018.https:\/\/www.kaypahoito.fi\/hoi38050(Accessed 3 October 2022)."},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f7027"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-4177"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2012-302983"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MJT.0000000000000551"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-021-04344-0"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000002845"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0000000000002260"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-016-1772-z"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix590"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-1340"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-011-1442-4"},{"key":"e_1_2_10_18_1","first-page":"2344","article-title":"Community antibiotic prescribing for children in France from 2015 to 2017: a cross\u2010sectional national study","volume":"75","author":"Trinh NTH","year":"2020","journal-title":"J Antimicrob Chemother"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.12051"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjid.2013.11.007"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2018.07.044"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000003693"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.16323"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.77.6.795"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2005.tb02076.x"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.107.4.619"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-2902"}],"container-title":["Acta Paediatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apa.16641","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/apa.16641","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apa.16641","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T05:09:45Z","timestamp":1749100185000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apa.16641"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,30]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1111\/apa.16641"],"URL":"https:\/\/doi.org\/10.1111\/apa.16641","archive":["Portico"],"relation":{},"ISSN":["0803-5253","1651-2227"],"issn-type":[{"value":"0803-5253","type":"print"},{"value":"1651-2227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,30]]},"assertion":[{"value":"2022-11-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}