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Kronprinsessan Lovisas F\u00f6rening f\u00f6r Barnasjukv\u00e5rd","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009757","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To study if stabilisation using a new respiratory support system with nasal prongs compared to T\u2010piece with a face mask is associated with less need for mechanical ventilation and bronchopulmonary dysplasia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A single\u2010centre follow\u2010up study of neonates born &lt;28\u2009weeks gestation at Karolinska University Hospital, Stockholm included in the multicentre Comparison of Respiratory Support after Delivery (CORSAD) trial and randomised to initial respiratory support with the new system versus T\u2010piece. Data on respiratory support, neonatal morbidities and mortality were collected up to 36\u2009weeks post\u2010menstrual age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ninety\u2010four infants, 51 female, with a median (range) gestational age of 25\u2009+\u00a02 (23\u2009+\u00a00, 27\u2009+\u00a06) weeks and days, were included. Significantly fewer infants in the new system group received mechanical ventilation during the first 72\u00a0h, 24 (52.2%) compared with 35 (72.9%) (<jats:italic>p<\/jats:italic>\u00a0=\u20090.034) and during the first 7\u2009days, 29 (63.0%) compared with 39 (81.3%) (<jats:italic>p<\/jats:italic>\u00a0=\u20090.045) in the T\u2010piece group. At 36\u2009weeks post\u2010menstrual age, 13 (28.3%) in the new system and 13 (27.1%) in the T\u2010piece group were diagnosed with bronchopulmonary dysplasia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Stabilisation with the new system was associated with less need for mechanical ventilation during the first week of life. No significant difference was seen in the outcome of bronchopulmonary dysplasia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.16665","type":"journal-article","created":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T04:10:53Z","timestamp":1673410253000},"page":"719-725","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Respiratory outcomes after delivery room stabilisation with a new respiratory support system using nasal prongs"],"prefix":"10.1111","volume":"112","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2264-7449","authenticated-orcid":false,"given":"Sonja","family":"Baldursdottir","sequence":"first","affiliation":[{"name":"Department of Women's and Children's Health Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Neonatology Astrid Lindgren Children's Hospital, Karolinska University Hospital  Stockholm 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Children's Health Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Anaesthesiology \u00d6stersund Hospital  \u00d6stersund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baldvin","family":"Jonsson","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Neonatology Astrid Lindgren Children's Hospital, Karolinska University Hospital  Stockholm 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