{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T06:35:36Z","timestamp":1767162936411,"version":"build-2238731810"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100010628","name":"Universidad de La Sabana","doi-asserted-by":"publisher","award":["MED\u2010344\u20102023"],"award-info":[{"award-number":["MED\u2010344\u20102023"]}],"id":[{"id":"10.13039\/501100010628","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The aim of the study was to determine whether overcooling (temperature &lt;33\u00b0C) during passive hypothermia when transporting neonates with perinatal asphyxia increased the risk of short\u2010term neurological injury.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective observational study was performed. Newborns transferred to the LaCardio neonatal unit between January 2021 and April 2022 with moderate and severe perinatal asphyxia and who received passive hypothermia during transport were included. A temperature of &lt;33\u00b0C was considered overcooling. A composite outcome of neurological injury was defined by the presence of abnormalities on brain magnetic resonance imaging, video telemetry, seizure before discharge or both.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study included 101 newborns. A total of 18 neonates had a temperature &lt;33\u00b0C after transportation. Neurological injuries were present in 21.8% of the temperature &lt;33\u00b0C group and 78.2% of the temperature \u226533\u00b0C group. Temperature &lt;33\u00b0C at the end of transport (aOR 9.2, 95% CI 1.1\u201377.3) were associated with neurological injury before discharge from the unit.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>During transportation, overcooling in neonates with asphyxia increases the risk of neurological injury before discharge from the neonatal unit. It is important to qualify the transport team with adequate training and equipment for therapeutic hypothermia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.16921","type":"journal-article","created":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T06:05:20Z","timestamp":1690178720000},"page":"2346-2351","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Short\u2010term neurological injury in newborns infants with overcooling in passive hypothermia and transferred to reference hospital in Colombia"],"prefix":"10.1111","volume":"112","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1980-5656","authenticated-orcid":false,"given":"Gloria","family":"Troncoso","sequence":"first","affiliation":[{"name":"Neonatal Intensive Care Unit Fundaci\u00f3n Cardioinfantil\u2010LaCardio  Bogota Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9154-4529","authenticated-orcid":false,"given":"Sergio","family":"Agudelo\u2010P\u00e9rez","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit Fundaci\u00f3n Cardioinfantil\u2010LaCardio  Bogota Colombia"},{"name":"Department of Pediatrics, School of Medicine Universidad de La Sabana  Chia Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9495-3649","authenticated-orcid":false,"given":"Nicole","family":"Thorin","sequence":"additional","affiliation":[{"name":"School of Medicine Universidad de La Sabana  Chia Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8003-1271","authenticated-orcid":false,"given":"Camila","family":"Diaz","sequence":"additional","affiliation":[{"name":"School of Medicine Universidad de La Sabana  Chia Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9790-8941","authenticated-orcid":false,"given":"Alejandra","family":"Vargas","sequence":"additional","affiliation":[{"name":"School of Medicine Universidad de La Sabana  Chia Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/FPED.2019.00489"},{"key":"e_1_2_10_3_1","first-page":"325","volume-title":"Volpe's Neurology of the Newborn","author":"Terrie EI","year":"2018"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.PEDNEO.2016.11.001"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60496-7"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/APA.16133"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.SINY.2021.101259"},{"key":"e_1_2_10_8_1","first-page":"15","article-title":"Caracterizacion de los recien nacidos con asfixia perinatal en un Hospital Universitario de tercer nivel en Colombia","volume":"2","author":"Mu\u00f1oz J","year":"2013","journal-title":"Gastrobrup"},{"key":"e_1_2_10_9_1","unstructured":"AndreaM HerediaP Soto BoteroJ.CARACTERIZACI\u00d3N de un GRUPO de NI\u00d1OS con ASFIXIA PERINATAL que RECIBIERON HIPOTERMIA TERAP\u00c9UTICA. 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