{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T03:15:00Z","timestamp":1768619700534,"version":"3.49.0"},"reference-count":24,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T00:00:00Z","timestamp":1696204800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>We aimed to investigate the developmental outcome of children with Robin sequence (RS) for whom continuous positive airway pressure was the main strategy to release upper airway obstruction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included children with isolated RS or RS associated with Stickler syndrome who were aged 15\u2009months to 6\u2009years. We used the French version of the Child Development Inventory and calculated the developmental quotient (DQ) for eight different domains and the global DQ (DQ\u2010global). We searched for determinants of risk of delay.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 87 children, for 71%, the developmental evolution was within the norm (DQ\u2010global \u226586 or \u2265\u22121 SD), 29% were at high risk of delay (DQ\u2010global &lt;86 or &lt;\u22121 SD), and only 3% were at very high risk of delay (DQ\u2010global &lt;70 or &lt;\u22122 SD). The DQs for expressive language and language comprehension were lower in our study population than the general population, but an improvement was noticed with the children's growth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Risk of a developmental delay was not greater for children with the most severe respiratory phenotype than the others. Children whose mothers had low education levels were more at risk than the others.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.16979","type":"journal-article","created":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T05:24:56Z","timestamp":1696310696000},"page":"2601-2610","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Developmental outcome of children with Robin sequence treated with the current Paris protocol"],"prefix":"10.1111","volume":"112","author":[{"given":"Alix","family":"Fleurance","sequence":"first","affiliation":[{"name":"General Paediatrics Unit Necker University Hospital  Paris France"},{"name":"Reference Centre for Rare Disease\u2013Centre de R\u00e9f\u00e9rence Maladies Rares \u00abSyndromes de Pierre Robin et troubles de succion\u2010d\u00e9glutition cong\u00e9nitaux\u00bb  Paris 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cong\u00e9nitaux\u00bb  Paris France"},{"name":"Paris Cit\u00e9 University  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaelle","family":"Malecot","sequence":"additional","affiliation":[{"name":"General Paediatrics Unit Necker University Hospital  Paris France"},{"name":"Reference Centre for Rare Disease\u2013Centre de R\u00e9f\u00e9rence Maladies Rares \u00abSyndromes de Pierre Robin et troubles de succion\u2010d\u00e9glutition cong\u00e9nitaux\u00bb  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romain","family":"Luscan","sequence":"additional","affiliation":[{"name":"Reference Centre for Rare Disease\u2013Centre de R\u00e9f\u00e9rence Maladies Rares \u00abSyndromes de Pierre Robin et troubles de succion\u2010d\u00e9glutition cong\u00e9nitaux\u00bb  Paris France"},{"name":"Ear Nose and Throat Unit  Paris 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