{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:41:00Z","timestamp":1747183260528,"version":"3.40.5"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The head circumference to chest circumference (HC\/CC) ratio has been used to identify low birth weight infants in developed countries. This study was conducted to examine whether the ratio could distinguish asymmetrical foetal growth restriction (FGR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective observational study was conducted with 1955 infants (50.5% male) born at term between 2016 and 2020 at Tokyo Metropolitan Toshima Hospital, Japan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We found that 120 (6.1%) had FGR. Their mean birth weight was 3052.1\u2009\u00b1\u2009367.3\u2009g, and their mean gestational age was 39.1\u2009\u00b1\u20091.1\u2009weeks. Logistic regression analysis showed that the association between the HC\/CC ratio and FGR had a regression coefficient of \u221220.6 (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.000). The linear regression analysis showed that the association between the HC\/CC ratio and the birth weight <jats:italic>z<\/jats:italic>\u2010score had a regression coefficient of \u22128.59 (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.000). The coefficient of correlation was \u22120.33 (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The receiver operating characteristic curve for detecting FGR showed that the area under the curve was 0.75 and the cut\u2010off value was 0.93, with sensitivity of 75.8% and specificity of 60.8%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study established the associations between HC\/CC ratio and FGR and birth weight <jats:italic>z<\/jats:italic>\u2010scores and confirmed that the ratio provided an easy way to detect FGR in term\u2010born infants.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.17015","type":"journal-article","created":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T13:29:06Z","timestamp":1698845346000},"page":"67-71","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The head circumference to chest circumference ratio provided an easy way to detect foetal growth restriction in term infants"],"prefix":"10.1111","volume":"113","author":[{"given":"Hiroki","family":"Saito","sequence":"first","affiliation":[{"name":"Department of Pediatrics Juntendo University Faculty of Medicine  Bunkyo\u2010ku Tokyo Japan"},{"name":"Division of Pediatrics Tokyo Metropolitan Toshima Hospital  Itabashi\u2010ku Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4097-5104","authenticated-orcid":false,"given":"Yayoi","family":"Murano","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Juntendo University Faculty of Medicine  Bunkyo\u2010ku Tokyo Japan"},{"name":"Division of Pediatrics Tokyo Metropolitan Toshima Hospital  Itabashi\u2010ku Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suga","family":"Ashikawa","sequence":"additional","affiliation":[{"name":"Division of Obstetrics and Gynecology Tokyo Metropolitan Toshima Hospital  Itabashi\u2010ku Tokyo 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