{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T05:51:41Z","timestamp":1794030701535,"version":"4.8.0"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,2,22]],"date-time":"2024-02-22T00:00:00Z","timestamp":1708560000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>A long\u2010acting monoclonal antibody against RSV (nirsevimab), given as an injection shortly after birth, is currently being rolled out globally. Carer acceptance of intra\u2010muscular (IM) vitamin K, another injection given shortly after birth, could serve to indicate the acceptability of nirsevimab.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analysed a national dataset of postnatal health visitor visits in Scotland; individual\u2010level data on gestation were not available. The primary outcome measure was the modality of administration of vitamin K; potential explanatory variables were maternal age, infant ethnicity, English as a first language, and measures of socio\u2010economic deprivation. We examined associations between IM vitamin K administration or oral\/no vitamin K and each explanatory variable.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From 2019 to 2021, questionnaires were available for 142\u2009857 infants; data was missing for 2.7%. IM Vitamin K uptake was high: 95.5% of carers consented, with 1.1% requesting oral vitamin K and 0.9% refusing vitamin K altogether. Infant ethnicity, use of English as a first language, socio\u2010economic status and maternal age were not associated with reduced uptake of IM vitamin K.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>If IM Vitamin K administration is a valid proxy measure for nirsevimab acceptance, we did not identify groups that might require increased engagement prior to nirsevimab roll\u2010out.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.17168","type":"journal-article","created":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T05:06:49Z","timestamp":1708664809000},"page":"1264-1269","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Uptake of intra\u2010muscular vitamin K administration after birth: A national cohort study"],"prefix":"10.1111","volume":"113","author":[{"given":"Susanne","family":"Brunton","sequence":"first","affiliation":[{"name":"Public Health Scotland  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynda","family":"Fenton","sequence":"additional","affiliation":[{"name":"Public Health Scotland  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pia","family":"Hardelid","sequence":"additional","affiliation":[{"name":"Great Ormond Street Institute of Child Health University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3866-1344","authenticated-orcid":false,"given":"Thomas C.","family":"Williams","sequence":"additional","affiliation":[{"name":"Department of Child Life and Health University of Edinburgh  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,22]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2309189"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2110275"},{"key":"e_1_2_13_4_1","unstructured":"New Medicine to Protect Babies and Infants from Respiratory Syncytial Virus (RSV) Infection. European Medicines Agency [Internet].https:\/\/www.ema.europa.eu\/en\/news\/new\u2010medicine\u2010protect\u2010babies\u2010and\u2010infants\u2010respiratory\u2010syncytial\u2010virus\u2010rsv\u2010infection"},{"key":"e_1_2_13_5_1","unstructured":"FDA Approves New Drug to Prevent RSV in Babies and Toddlers. FDA [Internet].https:\/\/www.fda.gov\/news\u2010events\/press\u2010announcements\/fda\u2010approves\u2010new\u2010drug\u2010prevent\u2010rsv\u2010babies\u2010and\u2010toddlers"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2023.28.49.2300686"},{"key":"e_1_2_13_7_1","unstructured":"UK Health Security Agency.Immunisation Against Infectious Disease.2023. The Green Book [Internet].https:\/\/www.gov.uk\/government\/collections\/immunisation\u2010against\u2010infectious\u2010disease\u2010the\u2010green\u2010book#the\u2010green\u2010book"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/hpeds.2019-0228"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1990.283"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejm199309233291301"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6601278"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.112.1.191"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.12887"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2017-3743"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10995-016-2205-8"},{"key":"e_1_2_13_16_1","unstructured":"Public Health Scotland.Child Health Pre\u2010school Review Coverage[Internet].2022.https:\/\/www.publichealthscotland.scot\/publications\/child\u2010health\u2010pre\u2010school\u2010review\u2010coverage\/child\u2010health\u2010pre\u2010school\u2010review\u2010coverage\u20102020\u2010to\u20102021\/"},{"key":"e_1_2_13_17_1","unstructured":"FraserE.Scottish Index of Multiple Deprivation 2020.2023. gov.scot [Internet].https:\/\/www.gov.scot\/collections\/scottish\u2010index\u2010of\u2010multiple\u2010deprivation\u20102020\/"},{"key":"e_1_2_13_18_1","volume-title":"R: A Language and Environment for Statistical Computing","author":"R Core Team","year":"2023"},{"key":"e_1_2_13_19_1","unstructured":"Public Health Scotland.Organisational Background\u2014Our Privacy Notice. Public Health Scotland [Internet].https:\/\/www.publichealthscotland.scot\/our\u2010privacy\u2010notice\/organisational\u2010background\/"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-1092"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980021003670"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10995-019-02846-w"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1003916"},{"key":"e_1_2_13_24_1","unstructured":"Public Health Scotland.Births in Scotland\u2014Year ending 31 March 2023\u2014Births in Scotland.2023. Public Health Scotland [Internet].https:\/\/publichealthscotland.scot\/publications\/births\u2010in\u2010scotland\/births\u2010in\u2010scotland\u2010year\u2010ending\u201031\u2010march\u20102023\/"},{"key":"e_1_2_13_25_1","unstructured":"WilliamsTC.VitK_Administration_Scotland.2024. 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