{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T05:55:01Z","timestamp":1785477301244,"version":"3.56.0"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T00:00:00Z","timestamp":1709596800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Genetic influences on cerebral activity have been described previously, but data are scarce in preterms. We aimed to investigate whether a genetic influence causes amplitude\u2010integrated electroencephalography (aEEG) signals to differ between singletons and twin preterm newborns.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective single\u2010centre study conducted at Innsbruck Medical University Hospital, Austria. Preterm infants born before 32\u2009weeks of gestation between 6 November 2010 and 6 December 2022 were eligible for the study. The aEEG was analysed for the total maturation score, its component scores and the number of sleep\u2013wake cycles per hour.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We enrolled 240 preterm twin infants (57.5% male) with a mean gestational age of 30 (range: 24\u201332) weeks and a mean birth weight of 1324 (range: 600\u20132116) grams. We compared 240 singleton matched preterms. No differences were found between preterm singletons and twin preterm infants regarding the total maturation and component scores, or the number of sleep\u2013wake cycles. aEEG showed no difference between monozygotic and dizygotic twins.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Compared to singletons, twin infants born preterm showed no differences in aEEG signals in the first 4\u2009weeks of life. Future studies should include more complex non\u2010invasive functional neuroimaging methods to gain more insight into this important topic.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.17190","type":"journal-article","created":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T11:15:28Z","timestamp":1709637328000},"page":"1356-1363","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Amplitude\u2010integrated electroencephalography showed no differences in cerebral activity between preterm singletons and twins in the first 4\u2009weeks of life"],"prefix":"10.1111","volume":"113","author":[{"given":"Christina","family":"Schreiner","sequence":"first","affiliation":[{"name":"Department of Pediatrics II (Neonatology) Medical University of Innsbruck  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Staudt","sequence":"additional","affiliation":[{"name":"Department of Pediatrics II (Neonatology) Medical University of Innsbruck  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0433-6196","authenticated-orcid":false,"given":"Ursula","family":"Kiechl\u2010Kohlendorfer","sequence":"additional","affiliation":[{"name":"Department of Pediatrics II (Neonatology) Medical University of Innsbruck  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9269-5756","authenticated-orcid":false,"given":"Elke","family":"Griesmaier","sequence":"additional","affiliation":[{"name":"Department of Pediatrics II (Neonatology) Medical University of Innsbruck  Innsbruck 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