{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:41:45Z","timestamp":1747183305634,"version":"3.40.5"},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of the nationwide study was to describe paediatric drug utilisation in Sweden.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Drug prescriptions dispensed to all children aged 0\u201317\u2009years in 2019 were analysed using data from the Swedish National Prescribed Drug Register.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We retrieved data on 2\u2009180\u2009508 unique children. Nearly 4.6\u2009million prescriptions were dispensed to children aged 0\u201317\u2009years, and 52% of these were to boys. Just under half of the children (47%) were dispensed at least one drug: 48% of girls and 45% of boys (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). More than a third (34%) were dispensed three or more different drugs during 2019. The number of dispensed prescriptions per 1000 children was higher in boys than girls up to 12\u2009years of age (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01), and the opposite trend was observed from 13\u2009years and above, even when we excluded contraceptives (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). The most common therapeutic areas were drugs for the respiratory tract (25%), namely antihistamines, antiasthmatics and cough medication. These were followed by psychoanaleptics and melatonin for the nervous system (19%) and dermatologicals (16%), namely cortisone creams and emollients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Paediatric drug use was common, and a considerable proportion of children were dispensed multiple drugs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.17305","type":"journal-article","created":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T08:44:40Z","timestamp":1717231480000},"page":"2147-2154","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Considerable paediatric drug dispensing \u2013 A nationwide study of more than 2\u2009million Swedish children"],"prefix":"10.1111","volume":"113","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5502-2405","authenticated-orcid":false,"given":"Elin","family":"Dahl\u00e9n","sequence":"first","affiliation":[{"name":"Swedish Medical Products Agency  Uppsala Sweden"},{"name":"Department of Clinical Science and Education Karolinska Institutet, S\u00f6dersjukhuset  Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9701-5895","authenticated-orcid":false,"given":"Elin Eyfells","family":"Kimland","sequence":"additional","affiliation":[{"name":"Swedish Medical Products Agency  Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2125.1999.00981.x"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12519-018-0186-y"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-009-0679-7"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjpo-2020-000880"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2023.113472"},{"key":"e_1_2_13_7_1","unstructured":"EU statistics on income and living conditions \u2013 children's level of general health.2021.https:\/\/ec.europa.eu\/eurostat\/statistics\u2010explained\/index.php?title=Health_statistics_\u2010_children. 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