{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:26:59Z","timestamp":1753878419468,"version":"3.41.2"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T00:00:00Z","timestamp":1719878400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To investigate the clinical feasibility of ultra\u2010high\u2010frequency abdominal ultrasound (UHFUS) scans of preterm and term infants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Prospectively, 19 healthy term newborn infants were examined with conventional ultrasound (CUS) (Toshiba, Aplio i700, linear probe 14L5) and UHFUS (Visualsonics VevoMD, linear probes UHF48 and UHF70) according to a standardised protocol. Measurements of wall thickness were performed for; stomach, small intestine, colon and peritoneum. Five preterm infants, with or without suspected necrotising enterocolitis (NEC), were also examined with UHF48. Of these, only one was later diagnosed with NEC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Differences between CUS and UHFUS (UHF48) were found in measurements of thickness; for peritoneum 0.25 versus 0.13\u2009mm (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), small intestine 0.76 versus 0.64\u2009mm (<jats:italic>p<\/jats:italic>\u2009=\u20090.039) and colon 0.7 versus 0.47\u2009mm (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) in healthy term infants. Gaining frequency from 46 to 71\u2009MHz showed a mean reduction in measurements of peritoneum from 0.13 to 0.09\u2009mm (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). One preterm infant with NEC showed a fivefold and twofold increase in peritoneal and gastrointestinal wall thickness respectively, compared to healthy preterm infants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>UHFUS was a clinically feasible, promising method with potential to improve gastrointestinal diagnostics in infants. Lower peritoneum thickness and gastrointestinal wall thickness were demonstrated with UHFUS compared to CUS, suggesting an overestimation by CUS.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.17342","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T15:36:34Z","timestamp":1719934594000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ultra\u2010high\u2010frequency ultrasound (48\u201370\u2009MHz) is a promising tool for improved gastrointestinal diagnostics in infants"],"prefix":"10.1111","author":[{"given":"Ronni Bengtson","family":"Jacobsen","sequence":"first","affiliation":[{"name":"Department of Paediatrics, Neonatal Department Aalborg University Hospital  Aalborg Denmark"},{"name":"Region V\u00e4stra G\u00f6taland, Department of Paediatrics, The Queen Silvia Children's Hospital Sahlgrenska University Hospital  Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanna","family":"Hebelka","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Queen Silvia Children's Hospital Sahlgrenska University Hospital  Gothenburg Sweden"},{"name":"Institute of Clinical Sciences, Sahlgrenska Academy University of Gothenburg  Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Gatzinsky","sequence":"additional","affiliation":[{"name":"Region V\u00e4stra G\u00f6taland, Department of Paediatrics, The Queen Silvia Children's Hospital Sahlgrenska University Hospital  Gothenburg Sweden"},{"name":"Department of Paediatrics, Institute of Clinical Sciences, Sahlgrenska Academy University of Gothenburg  Gothenburg 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