{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:27:34Z","timestamp":1753878454219,"version":"3.41.2"},"reference-count":26,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:00:00Z","timestamp":1720137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>Guidelines regarding voiding cystourethrogram (VCUG) indications following a paediatric kidney abscess are lacking. This study evaluates vesicoureteral reflux (VUR) prevalence and outcome after a first kidney abscess.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective study included all children presenting to a tertiary paediatric reference centre with de\u2010novo kidney abscesses from 2011 to 2022, diagnosed through imaging (ultrasonography or computed tomography). VCUG's clinical utility was assessed by exploring outcomes related to interventions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 17 patients (median age 9\u2009months, IQR; 6\u2009months\u20136\u2009years), VCUG identified VUR in 7 (41%; 95% CI: 18\u201365%), including two with grade IV\u2013V. Median abscess size was 19\u2009mm (IQR; 14\u201327). 7\/8 (88%) children with DMSA scan presented scars, including 4 with hypofunctioning (20%\u201344%), and one with a non\u2010functioning kidney. Scarring on the DMSA scan was similar regardless of identified VUR. Six children had subsequent pyelonephritis. Three of the remaining 11 had grade I\u2013III and two IV\u2013V VUR. Surgery was required in four children overall: three for recurrent pyelonephritis and one for high\u2010grade VUR and scars.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Among initial kidney abscess cases, 41% had VUR, similar to children experiencing their first uncomplicated pyelonephritis. VCUG results guided antibiotic prophylaxis but not surgical decisions. We suggest considering VCUG following recurrent pyelonephritis\/kidney abscess and\/or kidney scarring.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.17353","type":"journal-article","created":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T09:11:11Z","timestamp":1720170671000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Vesico\u2010ureteral reflux diagnosis after initial kidney abscess: Results from a Paediatric Tertiary Hospital"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7130-0439","authenticated-orcid":false,"given":"Evgenia","family":"Preka","sequence":"first","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, INSERM U970, PARCC, Paris Translational Research Centre for Organ, Transplantation  Paris France"},{"name":"N\u00e9phrologie P\u00e9diatrique, Centre de R\u00e9f\u00e9rence MARHEA, H\u00f4pital Universitaire Necker\u2010Enfants Malades, Assistance Publique \u2013 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