{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T06:00:17Z","timestamp":1783576817329,"version":"3.55.0"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T00:00:00Z","timestamp":1728000000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine the impact of the protocol change from slow to fast enteral feeding progression on duration of central venous catheter placement, and the rates of late\u2010onset sepsis and necrotising enterocolitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We compared the evolution of all very low\u2010birth\u2010weight infants admitted on their first postnatal day in neonatal intensive care unit during a 12\u2010month period, before (2021 Cohort) and after (2022 Cohort) implementation of a new feeding protocol. Linear regression model was used to adjust for confounding factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 343 VLBW infants were included (median gestational age\u2009\u00b1\u2009SD 28.3\u2009\u00b1\u20091.7\u2009weeks; median birth weight\u2009\u00b1\u2009SD 980\u2009\u00b1\u2009300\u2009g). Median initial duration of central venous catheter was 5\u2009days in 2022 cohort compared with 9\u2009days in 2021 cohort (unadjusted <jats:italic>p<\/jats:italic>\u2009=\u20090.006, adjusted <jats:italic>p<\/jats:italic>\u2009=\u20090.001). Median time to achieve full enteral feeding was 8\u2009days versus 12\u2009days, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, with no significant difference in late\u2010onset sepsis or necrotising enterocolitis rates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The change from slow to fast enteral feeding progression for very low\u2010birth\u2010weight infants significantly decreased the central venous catheter duration with no adverse outcomes. This is consistent with recent randomised study results and supports the safe implementation in neonatal intensive care units.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.17437","type":"journal-article","created":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T06:08:54Z","timestamp":1728022134000},"page":"370-377","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Providing very low\u2010birth\u2010weight infants with fast enteral feeding reduced how long they needed a central venous catheter"],"prefix":"10.1111","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9989-9919","authenticated-orcid":false,"given":"Laurie","family":"Benguigui","sequence":"first","affiliation":[{"name":"Department of Neonatology Women, Mothers and Children Hospital  Bron France"},{"name":"Lyon East Medical School University Claude Bernard Lyon 1  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Varnier","sequence":"additional","affiliation":[{"name":"Research on Healthcare Performance (RESHAPE), INSERM U1290 University Claude Bernard Lyon 1  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3257-6050","authenticated-orcid":false,"given":"Sophie","family":"Laborie","sequence":"additional","affiliation":[{"name":"Department of Neonatology Women, Mothers and Children Hospital  Bron France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franck","family":"Plaisant","sequence":"additional","affiliation":[{"name":"Department of Neonatology Women, Mothers and Children Hospital  Bron France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marine","family":"Butin","sequence":"additional","affiliation":[{"name":"Department of Neonatology Women, Mothers and Children Hospital  Bron France"},{"name":"Lyon East Medical School University Claude Bernard Lyon 1  Lyon France"},{"name":"International Centre for Infection Research, INSERM U1111, CNRS UMR5308 University Claude Bernard Lyon 1  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,4]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu11092029"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-1352"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)30552-4"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-0211"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu12030760"},{"issue":"3","key":"e_1_2_13_7_1","first-page":"199","article-title":"Efficacy of breast milk gastric lavage in preterm neonates","volume":"44","author":"Patel AB","year":"2007","journal-title":"Indian 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