{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T07:17:21Z","timestamp":1771485441486,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T00:00:00Z","timestamp":1728345600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine whether the use of less\u2010invasive surfactant administration (LISA) had changed between 2018 and 2024.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An online questionnaire was sent to all 191 neonatal units between June 2023 and May 2024. One consultant from each neonatal unit was randomly selected. Follow\u2010up was done by telephone (middle\u2010grade doctor grade and above or alternatively to Advanced Neonatal Nurse Practitioners) for the non\u2010responders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Response rate was 100%from 191\u2009units neonatal units. LISA was used in 134 (70%) neonatal units in 2024 compared to 35 (18.7%) units in 2018 (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The reason why LISA was not performed was lack of experience\/training (51%) or not having a standardised practice\/guideline (49%). LISA in the delivery suite (DS) had increased from 2% in 2018 to 16% in 2024, and the use of video laryngoscope for LISA is becoming standard of practice. The oxygen requirement criteria for the use of LISA in both the DS and on neonatal unit had reduced to FiO2 of 0.3 or more.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The uptake of LISA had increased in the United Kingdom. There is greater use of LISA in the DS. Lack of training and expertise were the major limiting factors for LISA not being performed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.17446","type":"journal-article","created":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T12:55:55Z","timestamp":1728392155000},"page":"393-397","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Changes in practice of less\u2010invasive surfactant administration (<scp>LISA<\/scp>) in United Kingdom neonatal units"],"prefix":"10.1111","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7390-5228","authenticated-orcid":false,"given":"Sandeep","family":"Shetty","sequence":"first","affiliation":[{"name":"Neonatal Intensive Care Centre St George's University Hospitals NHS Foundation Trust  London UK"},{"name":"St George's University of London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donna","family":"Tolentino","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Centre St George's University Hospitals NHS Foundation Trust  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheryl","family":"Lau","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Centre St George's University Hospitals NHS Foundation Trust  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donovan","family":"Duffy","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Centre St George's University Hospitals NHS Foundation Trust  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8672-5349","authenticated-orcid":false,"given":"Anne","family":"Greenough","sequence":"additional","affiliation":[{"name":"Department of Women and Children's Health, Faculty of Life Sciences and Medicine, School of Life Course Sciences King's College London  London 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