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It also compared the symptoms experienced during different feeding methods, including percutaneous endoscopic gastrostomy (PEG).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The national expert team for children with SRS at Queen Silvia Children's Hospital, Gothenburg, studied 46 referrals (63% male) who were born with SRS in Sweden from 1984 to 2018. Patient data were extracted from the Paediatric National Growth Hormone Registry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The medical records covered a median of 68% of the time of the patients' childhood, with a median follow\u2010up of 9\u2009years. Their symptoms were most prevalent during infancy and decreased when they were toddlers. Feeding problems and gastrointestinal symptoms were reported in 91% of the 46 patients, with vomiting in 57% and constipation in 46%. There were 19 children who relied on enteral feeding for their nutrition and 13 of those received PEG. Their body mass index (BMI) increased significantly 2\u2009years after PEG started (<jats:italic>p<\/jats:italic>\u2009=\u20090.005).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Feeding problems and gastrointestinal symptoms were very common in children with SRS, but partly disappeared during childhood. Providing treatment, such as PEG, normalised the BMIs of children with SRS and reduced their symptoms.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apa.17474","type":"journal-article","created":{"date-parts":[[2024,10,26]],"date-time":"2024-10-26T05:35:13Z","timestamp":1729920913000},"page":"569-577","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Percutaneous endoscopic gastrostomy helped to normalise feeding problems and gastrointestinal symptoms in Silver\u2010Russell syndrome"],"prefix":"10.1111","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1562-2174","authenticated-orcid":false,"given":"Nataliia","family":"Muz","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy University of Gothenburg  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Petersson","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy University of Gothenburg  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Saalman","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy University of Gothenburg  Gothenburg Sweden"},{"name":"Region V\u00e4stra G\u00f6taland, Department of Pediatric Medicine Queen Silvia Children's Hospital  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9637-3439","authenticated-orcid":false,"given":"Jovanna","family":"Dahlgren","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy University of Gothenburg  Gothenburg Sweden"},{"name":"Region V\u00e4stra G\u00f6taland, Department of Pediatric Medicine Queen Silvia Children's Hospital  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,25]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmedgenet-2014-102979"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2016.138"},{"issue":"11","key":"e_1_2_12_4_1","article-title":"11p15 imprinting center region 1 loss of methylation is a common and specific cause of typical Russell\u2010Silver syndrome: clinical scoring system and epigenetic\u2010phenotypic correlations","volume":"92","author":"Netchine I","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2000.tb00357.x"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2001.tb00383.x"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2013-305864"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.14634"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2001.20058"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9103295"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2015-3951"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2011.05.017"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1991.tb11945.x"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(15)30423-6"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2005.41893.x"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1439-0280.2003.2c209.x"},{"key":"e_1_2_12_17_1","unstructured":"Socialstyrelsen.Karies bland barn ochungdomar. 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