{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T19:00:18Z","timestamp":1785438018018,"version":"3.56.0"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:00:00Z","timestamp":1731974400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:00:00Z","timestamp":1731974400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Infants born very preterm spend their early postnatal life in a neonatal intensive care unit, where irregular and unpredictable sounds replace the structured and familiar intrauterine auditory environment. Music interventions may contribute to alleviate these deleterious effects by reducing stress and providing a form of environmental enrichment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>This was an ancillary study as part of a blinded randomised controlled clinical trial entitled the effect of music on preterm infant's brain development. It measured the impact of music listening on the autonomic nervous system (ANS), we assessed heart rate variability (HRV) through high\u2010resolution recordings of heart rate monitoring, at three specific postmenstrual ages in premature infants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From 29 included subjects, 18 were assessed for complete HRV dataset, including nine assigned to the music intervention and nine to the control group. Postmenstrual age appeared to be the main factor influencing HRV from 33\u2009weeks to term equivalent age. Further analyses did not reveal any detectable effect of music intervention on ANS response.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study found that ANS responses were not modified by recorded music intervention in very preterm infants during wakefulness or sleep onset. Further research is warranted to explore other factors influencing ANS development in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.17500","type":"journal-article","created":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T08:29:19Z","timestamp":1732004959000},"page":"886-893","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of a music intervention on heart rate variability in very preterm infants"],"prefix":"10.1111","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7143-6117","authenticated-orcid":false,"given":"Francisca","family":"Barcos\u2010Munoz","sequence":"first","affiliation":[{"name":"Neonatal Intensive Care Unit University Hospital of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo I.","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Rennes University Hospital, Inserm  Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlene A.","family":"Abreu De Araujo","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit University Hospital of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Fau","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit University Hospital of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Filippa","sequence":"additional","affiliation":[{"name":"Swiss Center of Affective Sciences, Faculty of Psychology and Educational Sciences University of Geneva  Geneva Switzerland"},{"name":"Division of Development and Growth, Child and Adolescent Department University of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra S.","family":"H\u00fcppi","sequence":"additional","affiliation":[{"name":"Division of Development and Growth, Child and Adolescent Department University of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Beuch\u00e9e","sequence":"additional","affiliation":[{"name":"Rennes University Hospital, Inserm  Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Baud","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit University Hospital of Geneva  Geneva Switzerland"},{"name":"Inserm U1141 University Paris\u2010Cit\u00e9  Paris France"},{"name":"Department of Neonatal Medicine Cochin\u2010Port Royal Hospital, FHU PREMA, AP\u2010HP Centre  Paris 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