{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T18:59:52Z","timestamp":1785437992325,"version":"3.56.0"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T00:00:00Z","timestamp":1733702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T00:00:00Z","timestamp":1733702400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Monochorionic twins are at higher risk of perinatal mortality and morbidity, primarily due to pregnancy\u2010related complications, such as twin\u2010to\u2010twin transfusion syndrome (TTTS). We aimed to investigate whether amplitude\u2010integrated electroencephalography (aEEG) signals are different between monochorionic twins with and without TTTS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a retrospective single\u2010centre study conducted at Innsbruck Medical University Hospital, Austria. Preterm infants born before 32\u2009weeks of gestation between 6 November 2010 and 6 December 2022 were eligible. The aEEG was analysed for the total maturation score, its component scores and the number of sleep\u2013wake cycles per hour.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We enrolled 79 monochorionic twin infants (48% male) and 157 dichorionic (62% male) twin infants. We found no differences between these two groups of preterm infants regarding the total maturation and component scores, or the number of sleep wake cycles. Monochorionic twins with TTTS showed significantly lower total maturation scores and individual component scores compared to monochorionic twins without TTTS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Preterm infants with TTTS showed differences in neonatal aEEG signals. Whether these differences are caused by prematurity\u2010related or TTTS\u2010related factors, such as hemodynamic and metabolic changes due to placental anastomoses, should be investigated in future prospective studies, to gain more insight into this important topic.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.17532","type":"journal-article","created":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T13:19:51Z","timestamp":1733750391000},"page":"1022-1029","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Amplitude\u2010integrated electroencephalography showed alterations in cerebral activity in monochorionic twins with twin\u2010to\u2010twin transfusion syndrome"],"prefix":"10.1111","volume":"114","author":[{"given":"Christina","family":"Schreiner","sequence":"first","affiliation":[{"name":"Department of Pediatrics II (Neonatology) Medical University of Innsbruck  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Staudt","sequence":"additional","affiliation":[{"name":"Department of Pediatrics II (Neonatology) Medical University of Innsbruck  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6638-8624","authenticated-orcid":false,"given":"Vera","family":"Neubauer","sequence":"additional","affiliation":[{"name":"Department of Pediatrics II (Neonatology) Medical University of Innsbruck  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0433-6196","authenticated-orcid":false,"given":"Ursula","family":"Kiechl\u2010Kohlendorfer","sequence":"additional","affiliation":[{"name":"Department of Pediatrics II (Neonatology) Medical University of Innsbruck  Innsbruck 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