{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:44:34Z","timestamp":1787013874603,"version":"build-2736575974"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T00:00:00Z","timestamp":1734566400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T00:00:00Z","timestamp":1734566400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100010810","name":"\u00d6gonfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010810","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011831","name":"De Blindas V\u00e4nner","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011831","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005689","name":"G\u00f6teborgs L\u00e4kares\u00e4llskap","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005689","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2015\u201000810"],"award-info":[{"award-number":["2015\u201000810"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2016\u201001131"],"award-info":[{"award-number":["2016\u201001131"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2022\u201001562"],"award-info":[{"award-number":["2022\u201001562"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To investigate the association between retinopathy of prematurity and autism spectrum disorder in extremely preterm children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data in children born extremely preterm at &lt;28\u2009weeks\u2019 gestational age in the Region V\u00e4stra G\u00f6taland, 2013\u20132017, were analysed for association between retinopathy of prematurity and neurodevelopmental disorders. We focussed on autism spectrum disorder and excluded children with perinatal brain injuries or genetic disorders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 266 children with neurodevelopmental evaluation, 143 had no documented brain injury or genetic disorders. Of these 143, autism spectrum disorder was diagnosed in 18%, attention deficit hyperactivity disorder in 15% and intellectual disability in 7%. Of the 72\/143 children with a history of no or mild retinopathy of prematurity (stage &lt;1), 10% were diagnosed with autism spectrum disorder compared to 27% of 71\/143 with prior moderate\u2010to\u2010severe retinopathy of prematurity (stages \u22652), (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008). A history of retinopathy of prematurity stages \u22652 was associated with a threefold increased likelihood of later autism spectrum disorder even when adjusting for gestational age and sex (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.011).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Moderate\u2010to\u2010severe retinopathy of prematurity associated with a higher likelihood of later autism spectrum disorder diagnosis in extremely preterm children without documented brain injuries or genetic disorders.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.17539","type":"journal-article","created":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T05:37:55Z","timestamp":1734586675000},"page":"1161-1168","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Increased risk of autism in extremely preterm children with a history of retinopathy of prematurity"],"prefix":"10.1111","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7731-1988","authenticated-orcid":false,"given":"Pia","family":"Lundgren","sequence":"first","affiliation":[{"name":"The Sahlgrenska Centre for Pediatric Ophthalmology Research, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy University of Gothenburg  Gothenburg Sweden"},{"name":"Department of Ophthalmology Sahlgrenska University Hospital  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna B. K.","family":"Olsson","sequence":"additional","affiliation":[{"name":"Region V\u00e4stra G\u00f6taland, Child Psychology Unit and Dept of Neonatology, The Queen Silvia Children's Hospital Sahlgrenska University Hospital  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2224-3236","authenticated-orcid":false,"given":"Aldina","family":"Pivodic","sequence":"additional","affiliation":[{"name":"The Sahlgrenska Centre for Pediatric Ophthalmology Research, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy University of Gothenburg  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8563-2127","authenticated-orcid":false,"given":"Lena","family":"Jacobson","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience Karolinska Institutet and Karolinska University Hospital  Stockholm 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