{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T07:08:34Z","timestamp":1783840114483,"version":"3.55.0"},"reference-count":28,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T00:00:00Z","timestamp":1745280000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T00:00:00Z","timestamp":1745280000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["H30\u2010017"],"award-info":[{"award-number":["H30\u2010017"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["22FC2003"],"award-info":[{"award-number":["22FC2003"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Extremely low\u2010birthweight (ELBW) infants face an increased risk of physical, cognitive, and psychosocial challenges affecting health\u2010related quality of life (HRQoL). However, few studies have examined their long\u2010term prognosis in Japan. We aimed to assess the HRQoL of adolescents and young adults born with ELBW and identified associated factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A multicenter cross\u2010sectional study was conducted in Japan between January and March 2019. Adolescents and young adults born with ELBW completed the Japanese version of the Short Form Health Survey\u20108 and provided sociodemographic and health\u2010related data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 289 eligible participants, 169 (58.5%) returned the HRQoL questionnaire (129 self\u2010respondents and 40 proxy respondents). Proxy respondents had lower birth weights and higher rates of motor and neurodevelopmental impairment. Among self\u2010respondents, moderate\u2010to\u2010severe attention deficit hyperactivity disorder (ADHD) was associated with low physical (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.36, 95% CI \u22120.54 to \u22120.18,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and mental (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.29, 95% CI \u22120.48 to \u22120.10,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003) component summary scores, while motor impairment was associated with decreased physical component summary score (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.23, 95% CI \u22120.40 to \u22120.05,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.012).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ADHD and motor impairment are associated with low HRQoL. Long\u2010term evaluations and tailored support strategies are essential for this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.70104","type":"journal-article","created":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T05:37:48Z","timestamp":1747892268000},"page":"2270-2278","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Health\u2010Related Quality of Life in Japanese Youth Born Extremely Low\u2010Birthweight: Impact of Attention Deficit Hyperactivity Disorder"],"prefix":"10.1111","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5239-1830","authenticated-orcid":false,"given":"A.","family":"Moriichi","sequence":"first","affiliation":[{"name":"Division of Information for Specific Pediatric Chronic Diseases, Research Institute National Center for Child Health and Development  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Kono","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Jichi Medical University  Shimotsuke Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3148-9892","authenticated-orcid":false,"given":"S.","family":"Hirano","sequence":"additional","affiliation":[{"name":"Department of Neonatal Medicine Osaka Women's and Children's Hospital  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Hirasawa","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Tokyo Women's Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Toyoshima","sequence":"additional","affiliation":[{"name":"Department of Neonatology Kanagawa Children's Medical Center  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Hirose","sequence":"additional","affiliation":[{"name":"Department of Neonatology Seirei Hamamatsu General Hospital  Shizuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3027-602X","authenticated-orcid":false,"given":"T.","family":"Takayanagi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics NHO Saga Hospital  Saga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Cho","sequence":"additional","affiliation":[{"name":"Maternal and Perinatal Center Hokkaido University Hospital  Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,22]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.13880"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2020.101114"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ped.15493"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/children9030305"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2024.1480527"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41372-018-0061-7"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.3345\/cep.2020.01312"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1212\/CPJ.0000000000000920"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4733.2004.71273.x"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-0169"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.15249"},{"key":"e_1_2_15_13_1","volume-title":"Manual of the SF\u20108. 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