{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T22:37:11Z","timestamp":1790289431844,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,5,10]],"date-time":"2025-05-10T00:00:00Z","timestamp":1746835200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Hirschsprung's disease (HSCR) is a congenital disorder of the enteric nervous system, leading to functional intestinal obstruction in neonates and young children. This study aimed to assess the epidemiology and surgical management of HSCR in France over a 12\u2010year period using nationwide data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective cohort study using the French National Hospital Discharge Database (PMSI), including patients aged 0 to 3\u2009years diagnosed and surgically treated for HSCR between 2012 and 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 1512 patients, the average incidence was 17.26 per 100\u2009000 live births. Short\u2010segment disease accounted for 70% of cases, and 78.6% were male. A progressive shift toward minimally invasive techniques was observed, with laparoscopic surgery increasing significantly. Mortality was low (0.3%). Long\u2010segment disease was associated with higher reoperation rates and lower reoperation\u2010free survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study confirms the stable incidence of HSCR in France and highlights the increasing use of minimally invasive surgery. Regional disparities in care and the higher surgical burden in long\u2010segment cases underline the need for ongoing surveillance, equitable access and improved follow\u2010up strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.70127","type":"journal-article","created":{"date-parts":[[2025,5,10]],"date-time":"2025-05-10T05:31:19Z","timestamp":1746855079000},"page":"2526-2534","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Epidemiology and Surgical Management of Hirschsprung's Disease in France: A 12\u2010Year Retrospective Analysis (2012\u20132023)"],"prefix":"10.1111","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9506-7934","authenticated-orcid":false,"given":"Xavier Xu","family":"Wang","sequence":"first","affiliation":[{"name":"Clinical Research Center Centre Hospitalier Intercommunal de Cr\u00e9teil (CHIC)  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilguy","family":"Doisy","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Intercommunal de Villeneuve\u2010Saint\u2010Georges  Villeneuve\u2010Saint\u2010Georges France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seydou","family":"Goro","sequence":"additional","affiliation":[{"name":"Clinical Research Center Centre Hospitalier Intercommunal de Cr\u00e9teil (CHIC)  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadek","family":"Harichane","sequence":"additional","affiliation":[{"name":"Clinical Research Center Centre Hospitalier Intercommunal de Cr\u00e9teil (CHIC)  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathilde","family":"Rousseau","sequence":"additional","affiliation":[{"name":"Department of Medical Information CHIC  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Bellaiche","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology Robert Debr\u00e9 Hospital, Assistance Publique\u2013H\u00f4pitaux de Paris  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8486-8939","authenticated-orcid":false,"given":"Camille","family":"Jung","sequence":"additional","affiliation":[{"name":"Clinical Research Center Centre Hospitalier Intercommunal de Cr\u00e9teil (CHIC)  Cr\u00e9teil France"},{"name":"Department of Pediatrics CHIC  Cr\u00e9teil France"},{"name":"University of Paris\u2010Est Cr\u00e9teil  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2017.149"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sempedsurg.2022.151157"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2021.101765"},{"issue":"8","key":"e_1_2_10_5_1","first-page":"1319","article-title":"Hirschsprung's Disease: Diagnosis and Management","volume":"74","author":"Kessmann J.","year":"2006","journal-title":"American Family Physician"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.36740\/WLek202204220"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.5223\/pghn.2024.27.6.372"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sempedsurg.2022.151174"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.38.11.729"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2020.1711685"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2016-311872"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e328360c2a0"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/1093526619889436"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/JS9.0000000000000473"},{"issue":"1","key":"e_1_2_10_15_1","first-page":"80","article-title":"Total Transanal Endorectal Pull\u2010Through Versus Laparoscopic\u2010Assisted Approach in Children With Rectosigmoid Hirschsprung's Disease: A Systematic Review and Meta\u2010Analysis. 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