{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:33:33Z","timestamp":1791232413828,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100009804","name":"Svenska Diabetesstiftelsen","doi-asserted-by":"publisher","award":["2023\u201000063"],"award-info":[{"award-number":["2023\u201000063"]}],"id":[{"id":"10.13039\/501100009804","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>We aimed to investigate if the incidence of type 1 diabetes increased in children during the SARS\u2010CoV\u20102 pandemic and whether SARS\u2010CoV\u20102 antibodies were more frequently present at diagnosis compared with healthy individuals. We also examined whether clinical characteristics and coexisting autoimmunity differed between SARS\u2010CoV\u20102 antibody positive and negative individuals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective, longitudinal observational study included children aged 0\u201317\u2009years diagnosed with type 1 diabetes between 01 January 2018 and 31 December 2023 at Sk\u00e5ne University Hospital, Sweden. Blood samples were analysed for SARS\u2010CoV\u20102 antibodies and islet autoantibodies and compared to analyses of healthy children from the same period. Clinical characteristics and thyroid autoimmunity at onset were collected from medical records.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The incidence of type 1 diabetes increased from 40\/100.000 (pre\u2010pandemic) to 53\/100.000 (pandemic). Children diagnosed with type 1 diabetes more likely tested positive for SARS\u2010CoV\u20102 nucleocapsid protein (NCP) antibodies compared to healthy children. The SARS\u2010CoV\u20102\u2010NCP positive group had a higher prevalence of thyroid autoimmunity compared to the SARS\u2010CoV\u20102\u2010NCP negative group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The incidence of type 1 diabetes increased during the SARS\u2010CoV\u20102 pandemic, with a possible connection to COVID\u201019. Interestingly, children positive for SARS\u2010CoV\u20102 antibodies at type 1 diabetes diagnosis had a higher likelihood of thyroid autoimmunity compared to children negative for SARS\u2010CoV\u20102 antibodies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.70388","type":"journal-article","created":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T11:51:37Z","timestamp":1764589897000},"page":"713-723","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Increased Incidence of Type 1 Diabetes and Co\u2010Existing Thyroid Autoimmunity During the\n                    <scp>COVID<\/scp>\n                    \u201019 Pandemic in Sweden"],"prefix":"10.1111","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-7543-7852","authenticated-orcid":false,"given":"J.","family":"Anderberg","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences Lund Lund University  Lund 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