{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T16:12:52Z","timestamp":1778083972041,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002873","name":"Chulalongkorn University","doi-asserted-by":"publisher","award":["The 90th Anniversary of Chulalongkorn University Fund"],"award-info":[{"award-number":["The 90th Anniversary of Chulalongkorn University Fund"]}],"id":[{"id":"10.13039\/501100002873","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To assess the effect of antenatal dexamethasone on reducing the need for respiratory support in late preterm infants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The study was an open\u2010label randomised controlled trial. Participants included 294 pregnant women at risk of late preterm delivery, admitted to Da Nang Hospital for Women and Children, Vietnam. Women in the intervention group received antenatal dexamethasone, compared with standard care for the control group. Statistical analysis was conducted using STATA 18 with an intention\u2010to\u2010treat approach. Comparisons were performed using the chi\u2010squared test or Fisher's exact test for categorical data and the unpaired\n                      <jats:italic>t<\/jats:italic>\n                      \u2010test or Wilcoxon rank\u2010sum test for continuous data.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Infants in the control group required respiratory support after birth more frequently than those in the dexamethasone group (24.5% vs. 15%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04). The neonatal unit admission rate was significantly higher in the control group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01), with respiratory problems accounting for the most common reason for admission. Regarding morbidities, jaundice requiring phototherapy was significantly higher in the control group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Antenatal dexamethasone significantly reduced the need for respiratory support after birth and neonatal unit admission. Dexamethasone administration was not associated with increased maternal postnatal infection or neonatal hypoglycaemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrial.gov\">ClinicalTrial.gov<\/jats:ext-link>\n                      NCT 05841121\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.70417","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T19:02:36Z","timestamp":1766775756000},"page":"887-893","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Antenatal Dexamethasone on Respiratory Outcomes in Late Preterm Infants in a Vietnamese Tertiary Hospital: A Randomised Controlled Trial"],"prefix":"10.1111","volume":"115","author":[{"given":"Chau Hoang Minh","family":"Le","sequence":"first","affiliation":[{"name":"Da Nang University of Medical Technology and Pharmacy  Da Nang Vietnam"},{"name":"Faculty of Medicine Chulalongkorn University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hoang Thi","family":"Tran","sequence":"additional","affiliation":[{"name":"Da Nang Hospital for Women and Children  Da Nang Vietnam"},{"name":"Department of Pediatrics, School of Medicine and Pharmacy The University of Da Nang  Da Nang Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Quang Kim","family":"Huynh","sequence":"additional","affiliation":[{"name":"Da Nang Hospital for Women and Children  Da Nang Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surasith","family":"Chaithongwongwatthana","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Chulalongkorn University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,26]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"WHO \u201cThe Global Health Observatory \u201d(2022) https:\/\/www.who.int\/data\/gho\/data\/indicators\/indicator\u2010details\/GHO\/neonatal\u2010mortality\u2010rate\u2010(per\u20101000\u2010live\u2010births)."},{"key":"e_1_2_11_3_1","unstructured":"WHO \u201cNewborn Mortality \u201d(2022) WHO Newborn Mortality https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/levels\u2010and\u2010trends\u2010in\u2010child\u2010mortality\u2010report\u20102021."},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2006.01.009"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2019.1670796"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2018.04.003"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.50.4.515"},{"key":"e_1_2_11_8_1","article-title":"Antenatal Corticosteroids for Accelerating Fetal Lung Maturation for Women at Risk of Preterm Birth","volume":"12","author":"McGoldrick E.","year":"2020","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1516783"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2018.1554051"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2020.1808614"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.16677"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0248774"},{"issue":"6","key":"e_1_2_11_14_1","first-page":"374","article-title":"Antenatal Corticosteroid Therapy and Late Preterm Infant Morbidity and Mortality","volume":"81","author":"G\u00e1zquez Serrano I. 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