{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T11:08:38Z","timestamp":1775732918148,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:00:00Z","timestamp":1769040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:00:00Z","timestamp":1769040000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004063","name":"Knut och Alice Wallenbergs Stiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004063","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006738","name":"Medicinska Fakulteten, Lunds Universitet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006738","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009780","name":"Region Sk\u00e5ne","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>An electrocardiogram is commonly recommended in breath\u2010holding spell management, mainly to rule out long QT syndrome. This retrospective study investigated the risk of long QT syndrome being misdiagnosed as breath\u2010holding spells in a paediatric population in southern Sweden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data on patient characteristics and diagnostic findings were reviewed for patients aged &lt;\u200910\u2009years who were diagnosed with long QT syndrome between 2004 and 2018.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sixteen children were diagnosed with long QT syndrome; 10 were diagnosed through genetic screening, 4 following perinatal cardiac symptoms, and 2 due to episodes of syncope or seizures later diagnosed as epilepsy and breath\u2010holding spells. Three patients were\u2009&gt;\u200924\u2009months old at suspicion of long QT syndrome, and 10 were &lt;\u20093\u2009months old. No patient exhibited symptoms directly attributable to long QT syndrome, and no diagnosis of long QT syndrome was delayed due to suspicion of or misdiagnosis as breath\u2010holding spells.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The number of symptomatic long QT syndrome cases overlapping with the presentation of breath\u2010holding spells is likely small. The findings of this study suggest that children &lt;\u20093\u2009months old with suspected breath\u2010holding spells should undergo an electrocardiogram.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.70460","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T17:31:27Z","timestamp":1769103087000},"page":"1116-1125","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Population\u2010Based Study Found Low Risk of Misdiagnosing Long\n                    <scp>QT<\/scp>\n                    Syndrome as Breath\u2010Holding Spells in Swedish Children"],"prefix":"10.1111","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3424-0016","authenticated-orcid":false,"given":"Sanna Hellstr\u00f6m","family":"Schmidt","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Clinical Sciences Lund Lund University  Lund Sweden"},{"name":"Childhood Cancer Center Sk\u00e5ne University Hospital  Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5947-4759","authenticated-orcid":false,"given":"Ida","family":"Jeremiasen","sequence":"additional","affiliation":[{"name":"The Pediatric Heart Center Sk\u00e5ne University Hospital  Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik A.","family":"Eklund","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Clinical Sciences Lund Lund University  Lund Sweden"},{"name":"Department of Pediatric Neurology Sk\u00e5ne University Hospital  Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0073-9660","authenticated-orcid":false,"given":"Cornelis Jan","family":"Pronk","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Clinical Sciences Lund Lund University  Lund Sweden"},{"name":"Childhood Cancer Center Sk\u00e5ne University Hospital  Lund Sweden"},{"name":"Wallenberg Centre Molecular Medicine and Division Molecular Hematology Lund University  Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,22]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.04.044"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2020-318259"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2011.04.036"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2004.06.016"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.87.6.1866"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.22.2237"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-008-0896-6"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.119.043132"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(43)80257-2"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.107.2.265"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.39.4.563"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1969.tb01520.x"},{"issue":"1","key":"e_1_2_11_14_1","first-page":"59","article-title":"The Value of Neurologic and Cardiologic Assessment in Breath Holding Spells","volume":"30","author":"Yilmaz U.","year":"2014","journal-title":"Pakistan Journal of Medical Sciences"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.13556"},{"issue":"11","key":"e_1_2_11_16_1","first-page":"A4217","article-title":"Long\u2010Term Prognosis for Children With Breath\u2010Holding Spells","volume":"57","author":"Olsen A. 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