{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:28:25Z","timestamp":1790260105487,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>This study described the aetiological factors associated with neonatal seizures and the risks for adverse neurological outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We identified all infants born at \u2265\u200936\u2009weeks of gestation between 2009 and 2015 who were diagnosed with or treated for neonatal seizures and registered in the Norwegian Neonatal Network. Data from four nationwide registries provided information on perinatal factors and neurological outcomes until 5\u2009years of age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were 892 infants with seizures, which was an incidence of 2.2 per 1000 live births. More than half (58.5%) underwent electroencephalography monitoring and examinations. Mortality before discharge was 8.4% and deaths occurred a median of 5\u2009days after birth. The most frequent presumed aetiology for neonatal seizures was moderate to severe hypoxic\u2010ischaemic encephalopathy (25.1%). Of the 817 survivors, 115 (14.1%) were diagnosed with post\u2010neonatal epilepsy, 119 (14.6%) with cerebral palsy (CP), and 43 (5.3%) had both diagnoses. The epilepsy risk was greatest after neonatal encephalopathy with normal Apgar scores (40.9%) and the CP risk was greatest after an ischaemic stroke (29.9%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Neonatal seizures were associated with a high risk of mortality and about a quarter were later diagnosed with epilepsy and\/or CP. Improved access to electroencephalography and higher usage could improve diagnostics.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.70463","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T14:15:25Z","timestamp":1769696125000},"page":"1202-1209","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Neonatal Seizures Were Associated With Higher Mortality, Epilepsy and Cerebral Palsy in Term\u2010Born Children up to 5\u2009Years of Age"],"prefix":"10.1111","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-4524-8188","authenticated-orcid":false,"given":"Jostein","family":"Lappeg\u00e5rd","sequence":"first","affiliation":[{"name":"Department of Paediatric and Adolescent Medicine University Hospital of North Norway  Troms\u00f8 Norway"},{"name":"Research Group for Child and Adolescent Health, Department of Clinical Medicine University of Troms\u00f8, the Arctic University of Norway  Troms\u00f8 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrik B\u00e5tstrand","family":"Lyeng","sequence":"additional","affiliation":[{"name":"Research Group for Child and Adolescent Health, Department of Clinical Medicine University of Troms\u00f8, the Arctic University of Norway  Troms\u00f8 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ragnhild","family":"St\u00f8en","sequence":"additional","affiliation":[{"name":"Department of Neonatology St. Olav's Hospital  Trondheim Norway"},{"name":"Department of Clinical and Molecular Medicine Norwegian University of Science and Technology  Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dag","family":"Moster","sequence":"additional","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen  Bergen Norway"},{"name":"Department of Pediatrics Haukeland University Hospital  Bergen 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